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research Farmácia do Lago, Porto e nos Serviços Farmacêuticos do Nemocnica Akademika Ladislava Dérera (Kramáre Hospital), Eslováquia
This study consisted of a pharmacy master's thesis detailing practical experiences during a hospital and community pharmacy internship and scientific investigations into the off-label use of dutasteride for androgenetic alopecia and oral vaccines for urinary tract infection prophylaxis, emphasizing therapeutic applications and mechanisms of action.
research Efficacy of Dipterocarpus alatus oil combination with Rhinacanthus nasutus leaf and Garcinia mangostana pericarps against canine demodicosis
In this study, dogs with localized demodicosis showed notable improvement in dermatological lesions when treated with Dipterocarpus alatus oil combined with Rhinacanthus nasutus leaf extract, particularly by day 28 of post-treatment, with no observed allergic reactions or clinical signs.
research Mycobacterium avium subspecies hominissuis infection in a dog from Germany with multifocal alopecia, exfoliative dermatitis, hypercalcaemia and subsequent sebaceous atrophy
This study reports the first successful treatment of a dog infected with Mycobacterium avium subspecies hominissuis using antibiotics, with no zoonotic transmission observed.
research Therapeutic effects of topical Mycophenolate mofetil on hydroquinone-induced depigmentation in Guinea pigs and mice
This study found that mycophenolate mofetil can enhance skin pigmentation in vitiligo models by activating the WNT signaling pathway and increasing melanin-related gene expression.
research Veterinary Pharmacology
This study found that alkaloids isolated from Cucumis metuliferus fruit pulp demonstrated antiviral activity against IBDV in chicken embryo fibroblast cells and NDV in 10-day-old embryonated chicken eggs, while being non-cytotoxic.
research Incidence of Multidrug Resistance Escherichia Coli Bacteria in Broiler Chickens in Malang Regency
In this study, researchers identified high levels of multidrug resistance in E. coli samples from broiler chickens in Malang Regency, with all positive samples resistant to multiple antibiotics including Erythromycin, Bacitracin, and Amoxicillin.
research Exploring murE protein inhibitors of Tropheryma whipplei through pharmacoinformatic approaches incorporating solubility-enhancing formulation insights
This study identified three Ayurvedic compounds that may serve as potential treatments against the macrolide-resistant enzyme murE of *Tropheryma whipplei*, addressing challenges in treating Whipple disease.
research An Experimental Study of Morphofunctional Features of Hair Follicles Early Response in Cyclophosphamide-Induced Alopecia
In this study, researchers found that topical application of 3-β-methoxy-Δ18-oleanene (miliacin) in mice sped up the recovery of hair follicles damaged by cyclophosphamide, moving them into a new hair growth cycle more quickly compared to controls.
research Steroid-sparing effect of mycophenolate mofetil in the treatment of a subepidermal blistering autoimmune disease in a dog : clinical communication
This case report describes how a treatment with mycophenolate mofetil and prednisone may be effective in managing autoimmune subepidermal blistering dermatosis in dogs while allowing for steroid reduction.
research Successful management of multiple extrapulmonary complications associated withRhodococcus equipneumonia in a foal
This report describes the successful treatment of multiple extrapulmonary disorders from Rhodococcus equi pneumonia in a foal, emphasizing the importance of thorough diagnosis and targeted treatment.
research AB032. Development of new treatment modality for male infertility by using phytopharmaceuticals
This study explored the effects of MOTILIPERM on infertility in a rat model with varicocele and oxidative stress, reporting its potential therapeutic efficacy.
research Antihelminthic Drugs
This review discusses adverse reactions to antihelminthic drugs and highlights that levamisole, a common street cocaine adulterant, can cause serious side effects, including skin necrosis and vasculitis.
research EVALUATION OF THE EFFECT OF MILIACIN ON THE HAIR FOLLICLE CYCLE IN C57BL/6 MICE IN AN EXPERIMENTAL MODEL OF ANDROGENETIC ALOPECIA
Miliacin helps extend the hair growth phase in mice with hair loss.
research Pseudomonas aeruginosa heme metabolites biliverdin IXβ and IXδ are integral to lifestyle adaptations associated with chronic infection
This study found that biliverdin beta and delta, metabolites of heme, play a critical role in Pseudomonas aeruginosa iron acquisition and cooperative behaviors, which are crucial for the bacterium's long-term infection in cystic fibrosis patients, suggesting potential targets for new therapies.
research The effectiveness of acaricidal drugs in bovine psoroptosis
In a study conducted on a beef-producing farm, "Deltsid 7.5" was found to be the most effective treatment for psoroptic scab in cattle, eradicating acarian phases and restoring skin and hair by 28 days, outperforming macrocyclic lactone treatments.
research Experimental medication of equine ringworm due to Trichophyton equinum var. autotrophkum
This study found that povidone iodine, thiabendazole ointment, captan ointment, and Burroughs Wellcome Ringworm Ointment were effective against Trichophyton equinum var. autotrophicum in horses, but large-scale use may be limited by practicality and cost.
research Eribulin Effectiveness and Safety in Metastatic Triple-Negative Breast Cancer: A Narrative Review
This study reviewed evidence on eribulin's efficacy and safety for treating metastatic triple-negative breast cancer, highlighting variable survival outcomes and manageable safety profiles for both monotherapy and combination therapies.
research Immunosuppressive treatment for proliferative lupus nephritis
This review update suggests that mycophenolate mofetil may increase complete disease remission in proliferative lupus nephritis compared to intravenous cyclophosphamide, but with low certainty of evidence.
research Anticancer agents against malaria: time to revisit?
This opinion article explores the possibility of repurposing anticancer drugs, like methotrexate, as antimalarials, highlighting that toxicity might be manageable with appropriate dosing according to Paracelsus' law.
research High‐dose mizoribine treatment for adolescents with systemic lupus erythematosus
This study reported that high-dose mizoribin therapy may be effective and safe for managing steroid-dependent pediatric systemic lupus erythematosus but requires monitoring of serum uric acid levels due to potential side effects.
research Toxicity of the pharmaceuticals finasteride and melengestrol acetate to benthic invertebrates
This study found that finasteride and melengestrol acetate exhibit varying levels of toxicity to freshwater mussels, amphipods, and mayflies, but current environmental concentrations suggest minimal direct effects on these aquatic invertebrates.
research Novel anti-Mullerian hormone receptor 2 binding peptide prevents chemotherapy-related ovarian follicle loss in a mouse model
In this study, researchers developed and tested a novel peptide, AMHR2BP, which mimics the function of Anti-Müllerian hormone to protect ovarian follicles in mice, showing promise for preserving ovarian health during chemotherapy without causing toxicity.
research [Mycophenolate mofetil in induction and maintenance therapy for juvenile onset severe lupus nephritis].
This study found that mycophenolate mofetil is effective for both induction and maintenance therapy in children with severe lupus nephritis, significantly improving proteinuria and antibody levels, without renal flares during maintenance.
research Bis-Benzylisoquinoline Alkaloids Inhibit Porcine Epidemic Diarrhea Virus In Vitro and In Vivo
This study found that the natural alkaloid cepharanthine effectively inhibited porcine epidemic diarrhea virus infection in newborn piglets.
research CLORURO DE BENZALCONIO EN EL TRATAMIENTO DE LA DERMATOMICOSIS CAUSADA POR Trichophyton sp. EN EL CUY (Cavia cobayo)
This study found that a single application of 0.1% aqueous benzalkonium chloride solution effectively treated dermatomycosis caused by Trichophyton species in guinea pigs.
research Concurrent psoroptic mange and malasseziosis in a beetal goat
In this case study of a Beetal doe with severe skin lesions, the researchers diagnosed concurrent psoroptic mange and malasseziosis, and reported successful treatment with a combination of Ivermectin, antibiotics, and topical applications, leading to reduced skin lesions and new hair growth.
research Influence of Depigmenting Chemical Agents on Hair and Skin Color in Yellow (Pheomelanic) and Black (Eumelanic) Mice
This animal study observed that while topical MBEH and intraperitoneal phenol induced hair graying in eumelanic mice, they had little effect on pheomelanic mice, and amcinonide reduced certain epidermal melanocytes in both.
research Studies on lysosomes—XIII
This study found that stilbamidine and hydroxystilbamidine can inhibit the release of specific enzymes from lysosomes and mitochondria in rabbit liver at certain concentrations, with effects similar to cortisol and chloroquine.
research Zoonotic Majocchi's Granuloma of the Vulva.
In this case report, a woman's Majocchi's granuloma, linked to her pet guinea pig infected with Trichophyton mentagrophytes, improved significantly with a combination of terbinafine and ketoconazole cream.