Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that pen-type microwells enhanced hair follicle germ formation by promoting cell assembly, suggesting microwell array geometry significantly influences in vitro hair follicle development.

This study found that using a microwell array device to expand hair follicle stem cells in Matrigel significantly increased cell numbers and enhanced hair regeneration in mice.

In this study, researchers used a 3D printing technique to spatially pattern human dermal papilla cell spheroids in a collagen matrix, enhancing skin and hair regeneration in a mouse model, with notable upregulation of key genes for hair follicle formation compared to traditional cell cultures.

In this study, researchers developed a photocurable polyurethane resin for 3D printing, creating high-resolution elastomeric microwell arrays that effectively promote uniform spheroid formation and growth of A549 cells, which could aid in disease modeling and organoid research.

This study investigated the use of 3D cell culture technology to explore hair follicle regeneration, examining the impact of the 3D cellular environment on hair follicle morphogenesis and the effects of microwell depth on spheroid formation.

This study achieved a first by successfully forming large quantities of dermal papilla spheroidal microtissues, which retained their hair induction potential, using a micropatterned culture system.

This study found that prevelex coatings on microwell array devices enhanced the formation of uniform cell spheroids and enabled the development of hair follicles in tissue engineering applications.

This study demonstrated a method for large-scale preparation of self-sorted hair follicle germs in vitro, which successfully generated hair follicles when transplanted into the skin of nude mice.

This study investigated how 2D and 3D cell culturing methods influence hair follicle morphogenesis, finding that 3D cultures responded more expectedly to minoxidil while 2D cultures reacted better to DHT treatment, challenging the assumption that 3D cultures are always superior.

This study developed a new mask-free method using digital micromirror and microfluidic systems to create multicellular heterospheroids for drug screening, finding that heterospheroids exhibit higher drug resistance and combinatorial drugs are more effective than single drugs in cancer therapeutic applications.

This study found that exosomes from human dermal papilla cell cultures, particularly in an oxygen-permeable 3D environment, most effectively supported hair follicle stem cell maintenance and promoted hair follicle formation in vitro.

This study observed that dermal papilla cell aggregates showed increased viability and gene expression on softer 3D substrates, indicating the importance of substrate stiffness in cellular behavior.

This literature review discusses the challenges and potential strategies for creating fully functional hair follicles capable of active cycling, emphasizing the molecular mechanisms, signaling pathways, and innovative regenerative techniques, such as hair micropatterning and three-dimensional printing, crucial for optimizing hair follicle regeneration.

This study developed a method for generating germ-like tissues called bbHFGs, which efficiently promoted hair follicle formation in mice, potentially advancing hair regenerative medicine applications.

This study presents a novel, scalable method for preparing highly hair-inductive tissue grafts using a bioprinter, which enhances hair follicle regeneration in mice, although most hair shafts remained beneath the skin.

This study presents a bioprinter-based method for creating scalable, automated hair-inductive tissue grafts that showed improved hair shaft sprouting in mice by using suture guides to control orientation.

Cold Plasma shows promise for healing wounds by killing bacteria and helping tissue grow.

This study demonstrated that PEGDA hydrogel microwells successfully supported cell survival and proliferation while mimicking hair follicle architecture in vitro, suggesting a potential tool for hair follicle engineering.

In this study, researchers developed a microfluidics-based method for creating uniform, size-controlled stem cell spheroids that enhance osteogenic differentiation when encapsulated in alginate-RGD microgels.

In this study, researchers developed a multilayered gel bead culture model using a microgel-spotting device, successfully mimicking the early development of skin appendages and supporting in vitro hair follicle regeneration with structures resembling native hair follicles.

This study found that 3D cultured hair follicle-like constructs, which include keratinocytes and dermal papilla cells, showed improved gene expression and cell interactions relevant to hair follicle development.

This review outlines recent advancements in droplet-based microfluidic technology using food-grade emulsions to create diverse delivery systems by controlling droplet size, shape, and dispersity, while also discussing challenges in scaling these processes from laboratory to industrial applications.

In this review, researchers examined advanced sensing technologies and bioelectronic interfaces that could improve understanding of the skin–brain axis, highlighting challenges and strategies for integrating these platforms into models for studying skin and neural interactions.

In this study, hair follicle germs containing vascular endothelial cells showed improved hair regeneration and morphogenesis-related gene expression in mice, suggesting a promising strategy for hair regenerative medicine.

This review discusses recent advances in microfabrication and microfluidic technologies for improving the production of organoids and spheroids, but it reports no new experimental results.

3D-oxy exosomes may significantly boost hair growth, offering new treatment options for hair loss.

This study identified distinct human and bacterial protein profiles in sebaceous follicular casts, with acne samples showing proteins linked to inflammation and normal samples showing proteins involved in stress protection.

This study found that topical cilostazol promotes hair growth, enhances hair follicle activities, and may serve as a potential treatment for alopecia.

This study developed a triple drug delivery system using nanoparticles loaded with 5-fluorouracil, curcumin, and piperine to target breast tumors, demonstrating notable in vitro cytotoxicity and anti-metastatic potential in 3D tumor spheroids which suggests its promise for further preclinical evaluation.

This study reported that a novel chitosan/polyvinyl alcohol nanofiber sponge effectively enhances the hair follicle-inducing ability of dermal papilla multicellular spheroids in a mouse model.