TLDR Advanced technologies can improve understanding and monitoring of skin-brain interactions.
The review discusses the skin–brain axis, highlighting its role in dermatological and neurocutaneous disorders like alopecia. It emphasizes the need for advanced experimental approaches to study skin–neural interactions. Recent technological advances, such as microscale and nanoscale sensing technologies and bioelectronic interfaces, are explored for their potential to enhance real-time monitoring of neuronal activity and neuroimmune signaling. The review also addresses engineering challenges like biofouling and sensor drift, proposing strategies to overcome these issues and guide the development of next-generation platforms for studying the skin–brain axis.
32 citations
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