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Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Advanced human skin models improve drug development and could replace animal testing.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Testosterone may slow down wound healing and increase inflammation.

Early balding linked to higher heart disease risk.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Some patients developed skin inflammation after obesity surgery, and a medication called dapsone helped treat it.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Combining microsurgery with craniofacial reconstruction improves aesthetic results and reduces harm to the area where tissue is taken from.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

No true link between AGA and insulin resistance, but coexistence may worsen AGA.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.