74 citations
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January 2014 in “Journal of Investigative Dermatology” High kallistatin levels in diabetics worsen wound healing by blocking important cell signals.
8 citations
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April 2023 in “Advanced materials” In this study, implantable vascularized engineered thrombi using autologous whole blood improved skin wound healing in rats by promoting robust microcapillary networks and accelerating healing processes.
September 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this paper, the authors propose that a historical decline in dietary tin intake may contribute to cardiovascular issues and accelerate pattern hair loss by causing copper and zinc depletion, which impairs heart function and scalp circulation.
September 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this paper, the authors propose that a major reduction in dietary tin over the past century could be linked to increased cardiovascular issues and androgenetic alopecia, hypothesizing that tin deficiency disrupts heart function and scalp circulation by depleting copper and zinc.
May 2025 in “Journal of Clinical Medicine” This study suggests that women with alopecia have decreased microcirculation oscillations, which may imply neuroinflammation as a factor in the disease's pathogenesis.
April 2024 in “Lasers in medical science” This study reviews the use of lasers and light therapies as treatment options for managing the two most common types of alopecia—androegenetic alopecia and alopecia areata—highlighting that existing FDA-approved drugs like minoxidil and finasteride are partially effective, necessitating additional therapeutic approaches.
June 2026 in “Journal of Cutaneous and Aesthetic Surgery” This review proposes an anatomy-based framework for understanding recipient site scalp necrosis in hair transplantation, emphasizing regional vascular vulnerability and surgical factors, but does not provide new clinical results.
6 citations
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October 2016 in “Journal of Cellular Physiology” This study found that human dermal fibroblasts can promote the viability and proliferation of microvascular endothelial cells in vitro, revealing important interactions at play in hair growth.
4 citations
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January 2008 in “Facial Plastic Surgery” This article reviews postoperative strategies to improve aesthetic outcomes of skin paddles used in microvascular free tissue transfer for head and neck reconstruction but offers no new clinical results.
9 citations
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March 2016 in “Natural Product Research” This study found that baicalin promotes human microvascular endothelial cell proliferation, while visnadin and minoxidil enhance tubulogenesis, with hesperidin uniquely increasing VEGFR-2 phosphorylation compared to other compounds tested.
2 citations
,
January 2006 in “PubMed” This study found that topical application of carpronium chloride led to arteriolar vasodilation and increased blood flow in rat mesenteric arterioles, without affecting systemic blood pressure.
3 citations
,
October 1994 in “Medical Molecular Morphology” This study observed that the lower part of vibrissa hair roots in adult Wistar rats receives a richer blood supply and structural protection, compared to the upper part.
17 citations
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May 2013 in “Oral and Maxillofacial Surgery Clinics of North America” This article reviews the complex challenges of managing scalp and cranial deformities post-trauma or surgery, advocating for better multidisciplinary approaches to enhance outcomes, but reports no new results.
3 citations
,
January 2022 in “Burns & Trauma” This study found that CTHRC1 is crucial for sweat gland function and vascular network integrity in mice, and its administration improved sweat gland performance by reconstructing nearby blood vessels.
January 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” This review article highlights that obesity is a significant risk factor for several inflammatory skin conditions, such as psoriasis and atopic eczema, contributing to increased overall morbidity among those affected.
March 2023 in “International Journal of Advanced Research in Science, Communication and Technology” This article discusses various synthetic and herbal treatments for alopecia, noting limited effectiveness and associated side effects of synthetic options, and reports no new clinical results.
162 citations
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July 2011 in “Biomacromolecules” This study found that chitosan nanofibrillar scaffolds accelerated skin wound healing in mice by enhancing cell adhesion, proliferation, and regeneration of epidermis and dermis compared to other forms.
51 citations
,
October 1981 in “British Journal of Dermatology” This study found that in patients who underwent jejuno-ileal bypass for morbid obesity, dapsone was effective in treating inflammatory skin lesions and joint symptoms when other antibiotics failed.
February 2026 in “American Journal Of Pathology” Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
3 citations
,
October 2023 in “Journal of Pain” In this exploratory study of trigeminal neuralgia patients undergoing microvascular decompression surgery, differential protein expression in plasma and cerebrospinal fluid was observed between responders and non-responders, suggesting potential biomarkers to predict surgical success and providing insights into the mechanisms of pain relief.
December 2025 in “Molecules” This study found that the 15-PGDH inhibitor DPP improved endothelial function in hair-related cells exposed to DHT by reducing oxidative stress and enhancing angiogenic capacity.
March 2024 in “Case Reports in Ophthalmology” This case report describes a young, healthy patient experiencing central retinal vein occlusion with cystoid macular edema while taking minoxidil for hair loss, which resolved without intervention after stopping the drug, leading to a recommendation for thorough medication history evaluations in similar cases.
9 citations
,
November 2024 in “Journal of Wound Management Official journal of the European Wound Management Association” Cold Plasma shows promise for healing wounds by killing bacteria and helping tissue grow.
89 citations
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March 2001 in “Endocrine practice” This article provides diagnosis and treatment guidelines for hyperandrogenic disorders in women but reports no new clinical results; it offers a summary of accepted scientific information and suggestions for clinical practice.
December 2025 in “Experimental Dermatology” This study found that uric acid-linked microvascular dysfunction may play a role in alopecia areata, suggesting that targeting endothelial function and uric acid regulation could be a potential management strategy.
This review concluded that the efficacy of cosmeceutical hair serums for addressing hair loss lies in their use of bioactive peptides and plant compounds, like flavonoids and sterols, that target eight key contributing factors identified in hair loss conditions.
May 2024 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, it was observed that topical application of N,N-Dimethylglycine Sodium Salt significantly increased skin microcirculation and blood flow in human subjects, suggesting potential benefits for skin health and conditions like dermatitis.
July 1996 in “Annals of Internal Medicine” This letter discusses the importance of microvascular disease in renal arterioles as a common cause of renal failure progressing to end-stage renal disease, a topic often overlooked in nephrology literature.
September 2025 in “Clinical Cosmetic and Investigational Dermatology” This review highlights that while moderate physical activity benefits skin health by improving circulation and reducing stress, intense exercise or inadequate protective measures can harm the skin, emphasizing the need for sun protection and personalized care.
January 1998 in “Lasers in Surgery and Medicine” This study found that both 5-ALA and Photofrin can effectively destroy human microvascular endothelial cells in vitro and cause tissue necrosis in vivo, with Photofrin showing greater efficacy at lower concentrations or power densities.