October 2014 in “Microscopy” This study found that using ionic liquid for specimen preparation allowed for observation of dermal papilla cells and their cilia in near-living conditions, reducing damage typically caused by conventional preparation methods.
24 citations
,
December 1957 in “Experimental Cell Research” This study observed that the glassy layer of hair follicles in guinea pigs consists of thick collagen-type fibrils organized into two distinct arrays, whereas in young mice, the fibrils are thinner and develop between the outer root sheath and fibroblasts.
1 citations
,
August 2015 in “PubMed” This study discovered previously unknown structures in human hair shafts that may stabilize hair structurally and physicochemically.
January 2006 in “Dianzi xianwei xuebao” This study observed that ultrastructural changes like lamellar bodies and electron-dense granules in the stratum corneum may aid in the early diagnosis of Netherton syndrome.
January 2006 in “Chinese Journal of Dermatology” This study observed that amelanotic melanocytes from human hair follicles appeared morphologically immature, suggesting they might not transfer melanosomes into keratinocytes.
25 citations
,
October 1962 in “Journal of Ultrastructure Research” The hair follicle structure is more complex than thought, with new findings on protein formation.
3 citations
,
October 2022 in “Frontiers in Cell and Developmental Biology” This review explores the historical development of theories on physiological tissue regeneration, particularly focusing on peripheral nerve regeneration, and emphasizes the need for new experiments and perspectives without providing new empirical findings.
This study found that distinct hair fiber structures among blue fox, mink, and otter rabbit can be used to identify and differentiate these fur types.
15 citations
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January 1992 in “Sen'i Gakkaishi” This study suggests that the cell membrane complex in hair cuticles contains hydrophilic regions with disulfide bonds allowing polymer uptake and hydrophobic lamella-like lipid layers.
September 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers developed non-invasive methods to monitor hair shaft, melanin, and collagen dynamics in C57BL/6 mice across different hair follicle cycle phases, supporting non-invasive research in hair loss treatment development.
January 2000 in “Zhongguo yixue wulixue zazhi” This study observed that human hair keratin showed distinct morphological features depending on the dissolution speed, which could have potential applications in clinical settings for developing self-tendons.
101 citations
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July 1985 in “Journal of the American Academy of Dermatology” In this study, oral biotin improved hair growth, strength, and combability in a child with uncombable hair syndrome, while hair in two others slowly improved without biotin.
September 1989 in “PubMed” This study reported detailed three-dimensional ultrastructural observations of human hair and hair follicles using a modified preparation method, including morphological differences in hair bulb cell layers and surface projections on root sheath cells.
This study found that coconut oil may protect the cuticle of chemically treated hair, which tends to be damaged compared to untreated hair.
3 citations
,
July 2024 in “Annals of Biomedical Engineering” This study found that multiphoton microscopy imaging allows for detailed observation and quantitative analysis of collagen alterations in the progression of endometrial cancer, potentially offering a faster, more accurate method for early diagnosis compared to current protocols.
13 citations
,
September 2021 in “Communications Biology” This study introduces a five-modal microscopy technique that allows label-free, in vivo observation and quantitative analysis of various wound healing processes.
March 2012 in “Korean Journal of Microscopy” This study found that nanoparticles can penetrate the skin, but artifacts produced during specimen preparation complicate accurate observation, and proposed a method for reducing errors in imaging quantum dots as tracers.
35 citations
,
March 2012 in “Journal of dermatological science” This observational study aims to more accurately detect and localize Propionibacterium acnes in acne lesions by combining multiple microbiological visualization techniques, but it does not present new results on their causality to acne.
August 2024 in “Microscopy Research and Technique” This study described the structure of the hair brush on male Endoclita vietnamensis moths' legs, identifying characteristics such as specialized scales and a pheromone gland, which could facilitate the future development of pheromone-based pest control methods for eucalyptus pests in China.
77 citations
,
April 1999 in “Dermatologic Clinics” This article reviews how new observations have revolutionized surgical hair restoration and highlights the logical applications and prior illogical judgments that delayed this advancement, without reporting new results.
1 citations
,
November 1976 in “Archives of Dermatology” This article discusses the role of clinical observation and microscopic correlation in American dermatology training and reports no new clinical results.
7 citations
,
July 2017 in “Australasian Journal of Dermatology” This article evaluates reflectance confocal microscopy features of scalp melanoma but reports no new clinical results, suggesting further investigation is needed.
1 citations
,
January 2021 in “Pakistan journal of zoology” This study identified significant differences in medullary structure, hair length, and root diameter among dorsal guard hairs of red foxes, golden jackals, and gray wolves in Turkey.
25 citations
,
March 2002 in “Scanning” This study highlights confocal microscopy as a promising, minimally invasive tool for assessing hair morphology and internal structures, making it valuable for cosmetic hair assessments.
March 1995 in “The Journal of Dermatology” This study found that cultured hair apparatus cells initially showed low keratin antibody reactivity, which increased by day 6 as cells differentiated and corresponded with electron microscopic observations.
November 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” In this study, researchers administered Trigona bee honey to dogs with dermatitis and observed improvements in skin damage, including reduced inflammation, decreased erythema, and increased hair growth at alopecia sites, indicating its potential as a treatment for canine dermatitis.
20 citations
,
December 1995 in “Veterinary Dermatology” This study identified a marked reduction in melanin in the hair of Yorkshire Terriers with Colour Dilution Alopecia and proposed a new pathogenetic mechanism based on these observations.
2 citations
,
January 2023 in “Skin Appendage Disorders” In this study, chemotherapy-induced alopecia in cancer patients showed specific trichoscopic patterns and abnormal hair shaft morphology, suggesting intermittent follicle damage from chemotherapy, but larger studies are needed for confirmation.
1 citations
,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers developed a custom-designed 3D-printed microscope stage insert for inverted confocal microscopes, enhancing the accessibility of long-term intravital imaging of live cell dynamics in live transgenic mice, particularly in the skin.
1 citations
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December 2014 in “Scanning” This study used multiphoton microscopy to successfully visualize rabbit skin microstructure, highlighting its noninvasive potential for future skin research related to diseases and wound healing.