28 citations
,
August 2019 in “BMC Genetics” This study identified a target relationship between miR-148a, miR-10a, and BMP7, suggesting these microRNAs influence dermal papilla cell proliferation and may regulate hair follicle growth.
May 2023 in “Frontiers in chemistry” This study found that hair from the vertex posterior is a reliable sampling region for detecting zolpidem intake, showing consistent drug concentration and peak position compared to other scalp regions.
January 2023 in “Nanomedicine & nanotechnology open access” This review suggests that microneedling shows promise for improving hair quality, thickness, and density in treating androgenetic alopecia, but standardized treatment protocols are currently lacking.
June 2024 in “International journal of nanomedicine” This study highlights that current research efforts to deliver anti-acne drugs to hair follicles have primarily targeted healthy follicles, overlooking the distinct characteristics of pathologically clogged follicles in acne vulgaris.
24 citations
,
November 2015 in “Scientific reports” This study discovered a new region in the hair cortex where intermediate filaments are both aligned with the hair's axis and orientationally ordered, influenced by the cuticle boundary.
29 citations
,
September 2024 in “AAPS PharmSciTech” This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.
34 citations
,
May 2021 in “Journal of Nanobiotechnology” This study found that electrospun short fibrous sponges effectively mimic the 3D extracellular matrix, promoting tissue regeneration, angiogenesis, and wound healing in diabetic rats better than 2D fiber membranes.
15 citations
,
January 2016 in “Journal of cell science & therapy” This study found that autologous micro-grafts improved wound healing and reduced pain in leg ulcers unresponsive to routine treatments within one week, lasting up to a month.
March 2013 in “Revista Brasileira de Cirurgia Plástica” This article reviews advances in hair transplant techniques such as megasessions of micro and mini grafts, highlighting platelet growth factors' potential to enhance hair density, without reporting new clinical findings.
27 citations
,
March 2022 in “Forensic Toxicology” This review discusses micro-segmental hair analysis for forensic toxicology, emphasizing its potential to provide detailed drug distribution profiles and its application in investigations, while noting the method's limitations and future perspectives.
16 citations
,
April 2021 in “International Journal of Molecular Sciences” This study found that micro-current electrical stimulation may promote hair growth in human hair follicle-derived papilla cells and a mice model by enhancing cell proliferation, migration, and activating key growth pathways.
This study reports that a novel ketoconazole-loaded microneedle array significantly enhances drug delivery and retention in the skin, demonstrating improved hair growth in animal models, suggesting a promising treatment for androgenic alopecia that addresses current topical therapies' limitations.
149 citations
,
June 2010 in “The FASEB journal” In this study, miR-31 was found to play a significant role in hair cycle regulation in mice by controlling key gene expressions involved in hair growth and differentiation.
53 citations
,
February 2020 in “Expert Opinion on Pharmacotherapy” This review discusses pharmacologic and non-pharmacologic treatments for androgenetic alopecia, noting that current medications like finasteride and minoxidil can slow hair loss but only partially restore hair growth, with early treatment offering better outcomes.
127 citations
,
January 2013 in “PLOS ONE” This study found that feeding aged mice a probiotic yogurt induced changes leading to thicker, healthier fur, suggesting a bacteria-triggered interleukin-10-dependent mechanism that mimics signs of youth and reproductive fitness.
March 2026 in “Biomolecules” This review highlights the critical role of microRNAs in regulating hair follicle biology, significantly impacting wool and cashmere development by modulating gene expression and signaling pathways in sheep and goats.
48 citations
,
February 2025 in “Nano-Micro Letters” This review summarizes the application of microneedles in treating various skin diseases and highlights challenges like low drug loading, noting no new clinical results are reported.
January 2026 in “Nano-Micro Letters” This review discusses the principles, materials, and applications of melt electrowriting-based 4D printing for creating biomimetic scaffolds, but reports no new clinical results; it highlights recent advancements and remaining challenges in the field.
August 2025 in “Aesthetic Plastic Surgery” This review explores the mechanisms, current products, challenges, and innovative approaches related to cosmetics for hair loss prevention and growth promotion, emphasizing the need for multidisciplinary cooperation to enhance product development and market success.
13 citations
,
August 2007 in “Bioorganic & medicinal chemistry letters” This study developed a new competitive 5alpha-reductase inhibitor with an IC(50) of 0.84 microM using a novel chemical structure.
September 2019 in “University of Huddersfield Repository (University of Huddersfield)” In this study, nanoemulsion formulations were found to significantly enhance the skin retention of the antiseptic agent triclosan, with the optimal mixture being a low surfactant concentration, as demonstrated through quantitative and qualitative analysis using tape-stripping and micro CT scans.
19 citations
,
December 2015 in “Journal of Materials Chemistry B” This study found that using layer-by-layer encapsulation techniques on dermal papilla cells can support their function and may help treat hair loss when used in conjunction with freshly isolated epidermal cells.
11 citations
,
July 2021 in “Physiologia Plantarum” In this study, the gene SlPHL1 was identified as a transcription factor in tomatoes that enhances phosphate starvation responses by upregulating specific genes.
4 citations
,
May 2005 in “Seminars in Plastic Surgery” This article discusses the development and refinement of the hair-micrografting technique in cosmetic surgery and reports no new clinical results.
21 citations
,
January 2023 in “Biomaterials Science” This study investigated the use of dissolving microneedle patches to improve the skin-lightening effects of alpha-arbutin and resveratrol, finding that the patches enhanced intradermal delivery and slightly decreased the melanin index without affecting skin hydration or causing irritation over 24 hours.
1 citations
,
July 2018 in “Elsevier eBooks” This review discusses the basic principles of hair pathology and findings in common types of alopecia but reports no new research results.
This Ph.D. project aims to evaluate the self-assembling potential of hair keratin extracts and study the cellular response to both crude and purified keratins, highlighting their potential applications from biomedical to water remediation.
89 citations
,
August 2008 in “Human genetics” This study found that the EDAR 1540T/C genetic variant is significantly associated with hair thickness variation in Japanese populations, enhancing previously observed associations in Southeast Asian groups.
35 citations
,
October 2004 in “Biology of Reproduction” This study found that dual 5α-reductase inhibition in rats led to decreased sperm motility and altered morphology, resulting in subfertility.
33 citations
,
April 2017 in “American journal of clinical dermatology” This study suggests that deep dermatophytosis is a distinct condition occurring in immunocompromised patients, characterized by nodules, an indolent course, and absence of follicular invasion, which resolves completely with systemic antifungal treatment.