39 citations
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February 2024 in “Small” This review discusses the evolution and development of smart and multifunctional microneedles, highlighting their potential future importance in medical applications, but it reports no new experimental results.
December 2023 in “Annales Pharmaceutiques Françaises” This study concluded that Trilayer Dissolving Microneedles show promise in enhancing Minoxidil delivery for treating alopecia areata by improving its bioavailability and reducing side effects.
46 citations
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January 2020 in “Research” This review discusses the design, properties, and potential applications of smart microneedles, with no new clinical results presented.
January 2024 in “ResearchWorks at the University of Washington (University of Washington)” This study found that while measuring zinc in hair did not allow calculation of individual hair growth rates, it effectively characterized zinc, lead, and mercury concentrations and improved methods for analyzing these exposures using LA-ICP-MS.
10 citations
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January 1985 in “PubMed” This study found that electron and proton microprobe analysis can reveal differences in element distribution within human hair and epidermis, although no significant water content differences were noted between atopic eczema and normal skin.
January 2022 in “Bio web of conferences/BIO web of conferences” This study concluded that the elemental composition of tail brush hair in newborn calves can indicate trace element supply to the fetus during the last months of pregnancy.
6 citations
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July 2005 in “Farmaco” This study developed a micellar electrokinetic capillary chromatography method for determining minoxidil in Rogaine and generic products, offering a simple and efficient alternative to HPLC.
353 citations
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May 2016 in “TrAC Trends in Analytical Chemistry” This review discusses recent advances in droplet microfluidics for chip-based technologies such as single-cell analysis, small-scale cell cultures, and high-throughput drug screening, and it reports no new results.
11 citations
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September 1999 in “Biological Trace Element Research” This study concluded that mineral element deficiencies in pregnant women may be alleviated with targeted nutrient supplementation, although mutual resistance and promotional effects among the supplements were observed.
71 citations
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December 1987 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” This review highlights the challenges of using hair mineral analyses as precise indicators of mineral status due to various influencing factors, suggesting they may be informative when combined with other indicators.
5 citations
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April 2023 in “Journal of Multidisciplinary Healthcare” This study found that chemical elements, particularly hair selenium, may indicate nutritional status in older adults, with variations observed by age and gender.
1 citations
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January 2018 in “Journal of microscopy and ultrastructure” In this study, researchers used SEM/SDD-EDS to identify waterborne minerals like calcium and aluminum in the scalp hair cuticle of individuals using treated or untreated water for hair washing, finding that prior application of coconut oil or conditioners can prevent calcium uptake.
January 2016 in “Journal of animal research” This study found significant correlations for copper and zinc levels between hair and plasma in Pomeranian and Labrador dogs, but no significant correlation for iron.
14 citations
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August 2016 in “Journal of nanomedicine research” This animal study found that biscuits fortified with zinc oxide nanoparticles improved growth, appetite, and hair growth in zinc-deficient rats more effectively than traditional zinc forms, without apparent toxicity.
6 citations
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March 1991 in “Journal of Radioanalytical and Nuclear Chemistry” Manganese levels in hair may be linked to multiple sclerosis.
May 2026 in “Microchemical Journal”
5 citations
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February 2013 in “Journal of Liquid Chromatography & Related Technologies” This study developed and validated a micellar electrokinetic chromatography method to determine finasteride stability, finding that the drug degrades under acidic, basic, and oxidative stress conditions.
In this study, researchers developed an AI-powered platform called VitaDetect, which screens for vitamin deficiencies using image analysis of nails, tongue, and skin, aiming to provide an accessible and early-stage detection tool in resource-limited settings.
19 citations
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September 1999 in “Talanta” New method measures minoxidil concentration faster, more accurately, and automatically.
This study developed and validated a method to analyze active ingredients like nicotinamide and tocopherol in hair nourisher products using HPLC, which may facilitate quicker market access for these products.
25 citations
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April 1972 in “American Journal of Clinical Nutrition” This study found that variations in chromium levels along individual hair shafts reflect changes in the individual's chromium nutritional status over time, rather than environmental exposure.
1 citations
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August 2025 in “Clinica Chimica Acta” 7 citations
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February 2020 in “Analytical and Bioanalytical Chemistry”
January 2021 in “Scandinavian journal of clinical and laboratory investigation” This study presents a method using liquid chromatography tandem mass spectrometry to quantify biotin in plasma and serum, and explores how high biotin intake can interfere with diagnostic immunoassays that utilize biotin-streptavidin technology, potentially leading to misdiagnosis of endocrine disorders.
This study found that PIXE microanalysis effectively detected and quantified trace element changes in hair shafts, revealing a marked decrease in copper after treatment for green hair syndrome.
September 2001 in “PubMed” This study developed a non-destructive X-ray fluorescence technique to quantitatively analyze elemental content in human hair and constructed a database of element concentrations in healthy Swedish, Caucasian individuals.
January 2004 in “Trace Elements Science” This study observed that hair levels of chromium, manganese, and copper were lower in diabetics compared to controls, while iron levels were higher.
1 citations
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May 2019 in “Annals of Medicine” In this study, researchers found that most food supplement labels in Portugal recommend daily mineral doses exceeding the EU's Recommended Daily Allowance, with some even surpassing the Tolerable Upper Intake Level, raising safety concerns regarding potential adverse effects.
18 citations
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January 1977 in “Annals of Nutrition and Metabolism” This article reviews inherited mineral and trace element disturbances and reports no clinical results; it highlights conditions like hypomagnesaemia and acrodermatitis enteropathica linked to impaired nutrient absorption.
January 2004 in “Weiliang yuansu yu jiankang yanjiu” This study found that diabetic individuals had significantly lower hair levels of chromium, manganese, and copper, but higher iron levels, compared to non-diabetic controls.