1 citations
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January 2025 in “BIO Integration” This review highlights that the combination of ultrasound and microneedles can enhance transdermal drug delivery by using physical and energy-driven mechanisms to improve drug penetration into deeper skin layers, with implications for precision medicine and chronic disease treatments.
June 2026 in “Discover Nano” This review discusses current treatment strategies for alopecia and highlights the potential of lipid-based nanoparticles to improve drug delivery to the scalp and hair follicles, noting their ability to enhance skin penetration and drug stability while outlining associated challenges and the need for further research.
December 2025 in “Aesthetic Surgery Journal” This study reviews the role of exosomes in regenerative aesthetics, highlighting their potential in treating conditions like photoaging and wound healing through mechanisms like matrix remodeling and immunomodulation, while also noting advancements in exosome isolation techniques and regulatory considerations.
32 citations
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June 2024 in “Pharmaceutics” This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.
8 citations
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May 2025 in “Dermatology and Therapy” This review discusses the use of topical and intralesional corticosteroids for treating alopecia areata, highlighting their efficacy and safety but noting recurrence and pain as limitations; no new clinical results are reported.
19 citations
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July 2019 in “Biomedical Microdevices” This review discusses the safety and potential adverse events of microneedling as both a medical and consumer product, noting the need for further understanding; no new clinical results are presented.
365 citations
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March 2021 in “Frontiers in Bioengineering and Biotechnology” This review discusses the potential of nanocarriers to enhance transdermal drug delivery and the combination of these carriers with physical methods, but it reports no new experimental results.
48 citations
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February 2025 in “Nano-Micro Letters” This review summarizes the application of microneedles in treating various skin diseases and highlights challenges like low drug loading, noting no new clinical results are reported.
2 citations
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April 2021 in “International Journal of Pharmaceutics” This study concluded that a liquid serum formulation delivered two fluorescent dyes to deeper follicular regions more effectively than nanoparticle systems.
26 citations
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April 2019 in “Journal of Cosmetic Dermatology” This review discusses the potential of herbal treatments like Saw palmetto, Green tea, and Rosemary as alternatives to conventional drugs for androgenetic alopecia, noting that these herbs may inhibit the 5-alpha-reductase enzyme and reduce hair loss with fewer side effects.
3 citations
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January 2019 in “Česká a slovenská farmacie” This review discusses various types of microneedles and their potential to expand the range of drugs delivered via the skin, but reports no new clinical results.
January 2018 in “Stem cells in clinical applications” This review discusses the potential of exosomes and the secretome in stem cell-based regenerative therapies but reports no new experimental findings.
62 citations
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July 2018 in “Lasers in Medical Science” In this review, the researchers highlight LED therapy as an emerging and safe treatment for skin inflammatory conditions, aging, and hair growth disorders, noting its integration into dermatological practice but emphasizing the need for more controlled studies to confirm its efficacy.
June 2026 in “Dermatology and Therapy” This review provides an analysis of topical treatments with clinically proven efficacy for managing hyperpigmentation and concludes that the most effective approach is using combined therapies that target multiple aspects of skin pigmentation physiology.
January 2025 in “RSC Pharmaceutics” Smart microneedles using advanced tech could improve psoriasis treatment.
April 2026 in “International Journal of Molecular Sciences” This narrative review highlights the need for diabetes-informed approaches to aesthetic dermatology as accelerated skin aging in diabetic patients complicates the safety and effectiveness of cosmetic procedures.
February 2009 in “Journal of the American Academy of Dermatology” November 2025 in “Journal of Clinical Medicine” This narrative review highlights innovations in regenerative medicine and longevity research within plastic surgery, emphasizing biological, ethical, and regulatory aspects. The study underscores the potential to extend healthspans while balancing these advances with ethical considerations and safety.
164 citations
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February 2019 in “Anais Brasileiros de Dermatologia” This study produced a guide for managing adult female acne, addressing its complex nature compared to teenage acne, and providing detailed recommendations on diagnosis and treatment. The authors noted that further research is needed to better understand the condition.
138 citations
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June 2023 in “Molecules” This review examines various skin pigmentation disorders, their causes, and potential treatments, detailing 25 plants, 4 marine species, and 17 clinically tested topical and oral medications for managing these conditions.
42 citations
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February 2021 in “Signal Transduction and Targeted Therapy” This review discusses potential cell sources and bioengineering strategies for regenerating hair follicles with functional cycling, reporting no new results.
October 2025 in “Indian Journal of Plastic Surgery” This review reports significant advancements in plastic surgery using stem cell therapies for aesthetic and reconstructive applications, including grafting and wound healing, though it underscores the need for continued research to address regulatory, ethical, and standardization issues.
3 citations
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July 2021 in “Aesthetic Plastic Surgery” This case series observed that the combination of platelet-rich plasma and fat grafting improved hair quality and density in patients with non-scarring alopecia, with effects visible by 12 weeks and sustained up to one year.
January 2024 in “Dermatology Review” This study found that combining platelet-rich plasma with 4% hydroquinone was more effective in reducing melasma symptoms than using hydroquinone alone.
January 2020 in “Elsevier eBooks” This chapter provides an overview of phytochemicals with properties to combat alopecia and discusses the potential of flavonoids, found in several herbs, as a safer alternative to synthetic hair loss treatments due to their long-term skin compatibility.
September 2016 in “Springer eBooks” This review discusses the application of mesenchymal stem cells and their secretory factors for skin and hair regeneration and reports no clinical results; the authors highlight the progress and call for practical applications.
January 2015 in “Springer eBooks” This chapter reviews the potential of adipose-derived stem cells for skin aging and hair loss treatments but reports no new experimental results; the authors highlight these stem cells as a promising regenerative resource.
17 citations
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December 2024 in “Journal of Cosmetic Dermatology” This source highlighted the promising potential of polynucleotides in aesthetic medicine but emphasized the need for rigorous, high-quality studies to validate their effectiveness and safety.
4 citations
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March 2023 in “Current Oncology” This study reviews current methods and emerging approaches to prevent and treat chemotherapy-induced hair loss, reporting that evidence-based research is needed to validate effective strategies, which could enhance cancer patients’ quality of life and treatment compliance.
108 citations
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August 2017 in “Clinical, Cosmetic and Investigational Dermatology” This review highlights microneedling's promise as an adjuvant therapy for enhanced drug delivery in dermatology, especially for conditions like atrophic scars and pigmentation disorders, though its efficacy for vitiligo is limited.