Skin Pigmentation Types, Causes and Treatment: A Review

June 2023 in “ Molecules ”

Amin Mahmood Thawabteh, Alaa Jibreen, Donia Karaman, Alà Thawabteh, Rafik Karaman

melanin hyperpigmentation hypopigmentation albinism melasma vitiligo Addison’s disease post-inflammatory hyperpigmentation anti-inflammatory medications antioxidants tyrosinase inhibitors

Studysummary This review examines various skin pigmentation disorders, their causes, and potential treatments, detailing 25 plants, 4 marine species, and 17 clinically tested topical and oral medications for managing these conditions.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on mdpi.com →

Discuss this study in the Community →

Research cited in this study

7 / 7 results

research Effect of Alpha-Tocopheryl Acetate, Retinyl Palmitate, and Phytantriol on Hair Protection

1 citations , December 2022 in “Journal of applied biological chemistry”

This study found that TRP-hair essence significantly protected and improved the quality of human hair, particularly against heat stress, by enhancing cuticle health and maintaining hair color.

research Coconut, Castor, and Argan Oil for Hair in Skin of Color Patients: A Systematic Review

2 citations , July 2022 in “PubMed”

This study found that coconut oil clinically helps with brittle hair and hair infestation, while evidence for castor and argan oils improving hair growth or quality is weak.

research Jojoba Oil: An Updated Comprehensive Review on Chemistry, Pharmaceutical Uses, and Toxicity

47 citations , May 2021 in “Polymers”

This review surveys the chemical composition and various uses of jojoba oil in medicine and industry but presents no new clinical results.

research An Overview of Herbal Alternatives in Androgenetic Alopecia

26 citations , April 2019 in “Journal of Cosmetic Dermatology”

This review discusses the potential of herbal treatments like Saw palmetto, Green tea, and Rosemary as alternatives to conventional drugs for androgenetic alopecia, noting that these herbs may inhibit the 5-alpha-reductase enzyme and reduce hair loss with fewer side effects.

research Essential Oils and Their Single Compounds in Cosmetics: A Critical Review

183 citations , January 2018 in “Cosmetics”

This review discusses side effects and allergy contact dermatitis caused by essential oils in cosmetic products and reports no new clinical results.

research Janus Kinase Inhibitors in Dermatology: A Systematic Review

116 citations , February 2017 in “Journal of the American Academy of Dermatology”

This systematic review found that Janus kinase inhibitors have shown beneficial effects for psoriasis and alopecia areata, with promising preliminary results in other skin conditions, though more research is needed to define dosing and safety profiles.

research Rapid Skin Repigmentation on Oral Ruxolitinib in a Patient with Coexistent Vitiligo and Alopecia Areata

157 citations , December 2015 in “Journal of the American Academy of Dermatology”

This case study reported significant but temporary hair regrowth and skin repigmentation in a patient with vitiligo and alopecia areata during treatment with oral ruxolitinib.