October 2023 in “Facial Plastic Surgery” This study discusses current treatments for androgenetic alopecia like minoxidil and finasteride and highlights emerging therapies including regenerative medicine and low-level laser therapy due to some patients not responding well to standard options.
January 2004 in “Dermatologic Surgery” This study found that storing hair micrografts in DMEM with apoptotic cell death inhibitors improved in vitro hair shaft elongation and reduced apoptosis, potentially enhancing micrograft transplantation outcomes.
10 citations
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January 2004 in “Dermatologic Surgery” This study found that storing hair follicle micrografts in HEPES-buffered DMEM with ACD inhibitors like aminoguanidine significantly increased hair shaft elongation compared to phosphate-buffered salt solution, suggesting improved viability for transplantation.
88 citations
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July 2019 in “International Journal of Molecular Sciences” In this study of patients with Androgenic Alopecia, micro-grafts containing HD-AFSCs resulted in significantly improved hair density and follicle count over 11 months compared to a saline solution, suggesting a potential alternative therapy for hair regrowth.
69 citations
,
April 2019 in “Biomedicines” This study found that hair thickness and density increased after treatment with human follicle mesenchymal stem cells and platelet rich plasma, associated with enhanced Wnt signaling and platelet derived growth factors.
January 2019 in “Springer eBooks” Micrografts are useful for healing wounds, regenerating bone and periodontal tissues, and improving hair transplantation outcomes.
41 citations
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January 2020 in “BioMed Research International” This study found that micrografts containing human hair follicle mesenchymal stem cells significantly increased hair count and density compared to placebo over 58 weeks in patients experiencing hair loss.
June 2019 in “Stem Cell Research” This study established a pluripotent stem cell line from a patient with androgenetic alopecia, which can potentially be used to study the disease's pathological mechanisms.
May 1993 in “Medical Clinics of North America” This article discusses male pattern alopecia and current hair replacement surgical techniques, without presenting new clinical findings.
2 citations
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August 1994 in “The Journal of Dermatologic Surgery and Oncology” This article discusses the hair transplantation process and product, but reports no new experimental results; the author is Leonard M. Dzubow.
29 citations
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September 2019 in “Stem Cells International” This study observed that a treatment combining platelet-rich fibrin and micrograft spray-on skin led to rapid and complete wound healing in both massive and chronic burn patients within an average of 7-10 days.
10 citations
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July 1997 in “Dermatologic Clinics” This article discusses the use of laser technology in hair transplantation and highlights its potential benefits and drawbacks, emphasizing its role in achieving natural results in cosmetic hair restoration.
December 2025 in “ADMET & DMPK” This review synthesizes recent research to propose a precision framework for treating androgenetic alopecia and alopecia areata based on genetic insights and pathway biology, highlighting the roles of androgen-receptor signaling, immune dysregulation, and emerging therapies like regenerative medicine and AI-assisted diagnostics.
June 2024 in “Archives of Dermatological Research” In this study, significant upregulation of the genes SFRP2 and PTGDS was found in bald hair follicles of female pattern hair loss patients compared to non-bald follicles, suggesting these genes may be biomarkers and play a role in hair loss for this condition.
December 2015 in “University of Birmingham Institutional Research Archive (University of Birmingham)” This study showed that regulation of adipose androgen generation via AKR1C3 may contribute to a cycle of hyperinsulinaemia and lipid accumulation in women with PCOS.
June 2026 in “Journal of Cosmetic Dermatology” This study found that a combined treatment using autologous scalp‐derived micrografts and allogeneic dental pulp stem cell‐derived conditioned medium was well-tolerated and improved hair characteristics in 69.5% of patients with male androgenetic alopecia, particularly increasing hair diameter and hair number per follicular unit.
22 citations
,
December 1998 in “Dermatologic Surgery” This study found that preserving hair micrografts in an enriched storage medium for five hours significantly increased their survival rate compared to those stored in saline.
6 citations
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July 2023 in “Diabetology” This study in an animal model found that Rigenera® technology's use of autologous micrografts improved wound healing in diabetic rats by increasing factors like VEGF-A, IL4, and IL10 while reducing TNF-α and oxidative stress.
77 citations
,
April 1999 in “Dermatologic Clinics” This article reviews how new observations have revolutionized surgical hair restoration and highlights the logical applications and prior illogical judgments that delayed this advancement, without reporting new results.
3 citations
,
November 2021 in “Clinical, Cosmetic and Investigational Dermatology” In this study, a single application of autologous cellular micrografts showed short-term favorable responses in up to two-thirds of patients with androgenetic alopecia.
November 2025 in “Cosmetics” This review discusses the clinical efficacy, safety, and mechanisms of Autologous Micrografting Technology for androgenetic alopecia, reporting significant short-term improvements in hair density and thickness.
This study found that plucked hair follicles exhibited a higher growth rate than conventional one-hair micrografts in vitro, suggesting they may be a less invasive alternative for hair transplantation.
January 2024 in “Pharmacy information” New treatments using stem cells and other methods show promise for promoting hair growth in androgenetic alopecia.
8 citations
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January 2016 in “Journal of fiber science and technology” This study found that cysteic acid generation during hair bleaching is diffusion-controlled, increasing with the square root of bleaching time, in both cuticles and cortex of human hair fibers.
2 citations
,
September 2022 In this study, researchers found that a PER3 gene SNP may be pathogenic for a new subtype of dyschromatosis universalis hereditaria, especially when combined with a SASH1 mutation.
November 2023 in “Bioengineering” This study found that autologous micrografts using AMT® technology effectively improved symptoms and mobility in patients with early-stage knee osteoarthritis, demonstrating safety and potential benefits at 1- and 6-months post-procedure.
15 citations
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July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses the potential of induced pluripotent stem cells (iPSCs) for generating skin components, particularly for genetic skin disorder modeling and gene-corrected regenerative therapies, but reports no new clinical results.
1 citations
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November 2009 in “Hair transplant forum international” This article discusses the history of modern hair restoration surgery beginning with Dr. Norman Orentreich's introduction of the macrograft technique in 1959 and reports no new clinical results.
7 citations
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July 2018 in “Stem cell research” This study reported that reprogramming keratinocytes from plucked hair provides an easy, non-invasive, and efficient method for generating pluripotent iPSCs without the need for medical professionals or operating rooms.
77 citations
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March 2001 in “Clinics in Dermatology” This article discusses treatment approaches for female pattern hair loss and concludes that available medical treatments are effective in reversing or stabilizing the condition in most cases of mild-to-moderate severity.