June 2023 in “Benha Journal of Applied Sciences” In this study, researchers isolated gram-positive bacteria from acne lesions in 50 patients, finding that Staphylococcus epidermidis, Staphylococcus aureus, Micrococcus luteus, and Leuconostoc mesenteroides were present at varying frequencies, indicating multimicrobial causes for acne vulgaris.
14 citations
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April 2022 in “Functional & Integrative Genomics” This study identified specific miRNAs and mRNAs involved in the development of secondary hair follicles in cashmere goats, particularly noting a targeted relationship between chi-miR-30e-5p and DLL4.
November 2025 in “Dermato” In this review, researchers synthesized contemporary findings about the human skin microbiome's influence on conditions like acne, aging, and hyperpigmentation, highlighting the potential of microbiome-informed strategies and treatments such as postbiotics and probiotics to improve dermatological outcomes.
March 2021 in “CRC Press eBooks” This review discusses the cosmetic applications and healing phases of microneedling and reports no new clinical findings; the authors highlight its use for skin and hair treatments without epidermal damage.
November 2018 in “Studies in Medical Sciences” This study found that Finasteride microemulsion gel significantly reduced acne lesions in men compared to a control treatment over three months.
8 citations
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June 2016 in “Journal of Cosmetic Dermatology” The study concluded that serum AMH is a useful tool for diagnosing polycystic ovarian morphology in women with persistent acne, potentially replacing transvaginal ultrasound, though it does not correlate with hyperandrogenemia.
April 2026 in “Journal of Cosmetic Dermatology” This review highlights the potential of combining microneedling with exosome therapy in treating various dermatological conditions, but emphasizes the need for more evidence regarding its safety and effectiveness.
11 citations
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October 2003 in “Contraception” 5 citations
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January 2016 in “Surgical and Cosmetic Dermatology”
50 citations
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January 2016 in “The Journal of Clinical Endocrinology and Metabolism” This study found that miRNA expression profiles in follicular fluid are altered in women with PCOS, with certain miRNAs potentially useful for distinguishing patient subtypes and contributing to understanding PCOS heterogeneity.
43 citations
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November 2018 in “Nature Communications” This genome-wide association study identified 20 genetic signals at 15 risk loci related to severe acne, revealing new insights into its genetic predisposition, particularly affecting skin structure and maintenance.
8 citations
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February 2010 in “Journal of Dermatology” This study observed that a topical liposome formulation of a 5‐α‐reductase inhibitor effectively reduced the size of treated sebaceous glands and induced apoptosis in a hamster model, suggesting potential benefits for acne treatment.
56 citations
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November 1958 in “The Journal of Cell Biology” This study used electron microscopy to identify a distinct dendritic cell in the human epidermis, similar to the melanocyte, with unique structural features and variable melanin content.
March 2025 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” In this case report, the authors found that pigmented demodicosis, caused by Demodex mites, led to facial hyperpigmentation in a 16-year-old male and showed significant improvement with oral isotretinoin and topical ivermectin treatment.
9 citations
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May 2013 in “European Journal of Dermatology” This article discusses eruptive vellus hair cysts, describing their clinical characteristics, and reports no new research findings.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, mice lacking the Mcpip1 gene in their myeloid cells did not develop SCC-like tumors but instead showed increased melanocyte activity and hair loss, indicating a distinct role for myeloid Mcpip1 in skin cancer development compared to keratinocyte Mcpip1.
7 citations
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May 1996 in “PubMed” This article outlines the clinical and histological features of milia grouped in plaques on a 59-year-old woman's face but reports no new research findings.
February 2026 in “Advanced Healthcare Materials” This study proposes a metal-organic gel-encapsulated microneedle system with antibacterial, anti-inflammatory, and pro-angiogenic properties for treating infected wounds, demonstrating potential for precise and adaptive management by targeting various stages of wound healing.
203 citations
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May 2017 in “Journal of controlled release” This review discusses completed and ongoing clinical studies on microneedle-based technologies for cosmetic, therapeutic, and diagnostic applications and reports no new clinical results.
March 2022 in “Egyptian Academic Journal of Biological Sciences. E, Medical Entomology and Parasitology” This review examines the potential pathogenicity of Demodex mites in skin disorders, considering systemic factors like immunological imbalance and microbiome changes, but reports no new clinical findings.
54 citations
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November 2017 in “Scientific Reports” In this study, researchers observed that hyperandrogenic PCOS patients exhibited distinct miRNA and TGFβ signaling gene expression patterns in granulosa cells, suggesting these factors may play a role in PCOS pathogenesis.
February 2025 in “Research Society and Development” This narrative review compiled evidence suggesting that microneedling can effectively and safely improve skin conditions like scars, hyperpigmentation, and aging, provided it is performed correctly, by stimulating collagen production and enhancing topical treatment penetration.
131 citations
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May 2015 in “Experimental Dermatology” This review explores the development and cosmeceutical applications of microneedles for skin treatment, without reporting new clinical results, emphasizing safety and public perception as key factors for commercialization.
June 2009 in “マテリアルインテグレ-ション” This review discusses the most popular non-surgical cosmetic procedures pursued by men and highlights the importance of sex-specific considerations in treating male cosmetic patients; it reports no new clinical results.
20 citations
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April 2020 in “Journal of advanced Biomedical and Pharmaceutical Sciences” This study investigated the use of methylene blue in a niosomal hydrogel for photodynamic treatment of acne and found that it led to significant improvement in inflammation compared to IPL treatment.
1 citations
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April 2021 in “Aesthetic Cosmetology and Medicine” This article reviews various applications and substances in mesotherapy for skin conditions and discusses the benefits of series treatments, reporting no new clinical results.
June 2022 in “Indian Dermatology Online Journal” This case report describes a 19-year-old male with alopecia totalis and comedones over the bald scalp, suggesting the importance of terminal hair for sebum drainage to prevent preliminary acne lesions.
9 citations
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September 2022 in “Frontiers in Physics” This study found that Mueller Matrix microscopy can accurately identify, detect, and evaluate hair follicles in mouse skin tissue, suggesting its potential for skin structure research and dermatological applications.
7 citations
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January 2013 in “Ophthalmic plastic and reconstructive surgery” This case report describes a rare instance of late-onset, bilateral nevus comedonicus of the eyelids in a 79-year-old man, highlighting its clinical and histopathologic features.
91 citations
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August 2024 in “Acta Pharmaceutica Sinica B” This review explores how microneedles can improve the delivery of dermatological treatments by bypassing the skin's outer barrier, discussing their potential use in managing skin diseases, cosmetic applications, and challenges related to clinical adoption.