January 2026 in “Dermatologic Therapy” This study found that a hair serum containing Acanthus ebracteatus extract improved hair regrowth in men with androgenic alopecia, increasing hair count and density of anagen hairs over a 6-month period, with combination treatments showing early effectiveness.
323 citations
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November 2017 in “Bioanalysis” This commentary discusses the challenges of matrix effects in LC–MS analysis and introduces the concept of a matrix effect factor using stable isotopically labeled internal standards to improve analysis reliability.
58 citations
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January 2015 in “International Journal of Trichology” This review evaluates the therapeutic potential of platelet-rich plasma for treating non-cicatricial alopecias and suggests it may be effective, though further research is needed to confirm its efficacy.
38 citations
,
April 2018 in “Diseases” This study observed that fibrin rich in leukocytes and platelets (L-PRF) might effectively heal diabetic foot ulcers with osteomyelitis, showing positive preliminary results in all three patients treated.
36 citations
,
April 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that canine bulge-derived keratinocytes are highly proliferative and can reconstitute pilosebaceous structures, indicating their potential utility in studying human stem cell biology and hair disorders.
30 citations
,
December 2014 in “BMC Genetics” This study found thousands of differentially expressed genes and proteins that may be associated with wool growth, suggesting potential gene families involved in hair growth regulation.
24 citations
,
July 2015 in “International Journal of Molecular Sciences” In this study, fluoxetine was found to decrease proliferation and adipogenic differentiation of human adipose-derived stem cells, suggesting it may reduce fat accumulation by increasing autophagy-related gene expression.
21 citations
,
December 2022 in “Pharmaceutics” This review found that laser-assisted drug delivery in humans was associated with several adverse effects, but no life-threatening events were reported in the studies examined.
13 citations
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July 2020 in “Stem Cell Research & Therapy” This study identified a comprehensive global landscape of stemness-related gene clusters in adipose-derived mesenchymal stem cells, revealing that stemness was highest in cells from young donors and lowest in those from elderly donors.
8 citations
,
July 2020 in “Applied Sciences” This review discusses the strengths and weaknesses of existing studies on complex dietary supplements for hair loss, emphasizing the need for valid measurement methods like TrichoScale® to quantify effectiveness; it reports no new results.
7 citations
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May 2024 in “Life” This study found no significant laboratory differences between Caucasian adults with non-cicatricial alopecia and healthy controls, but reported that affected individuals were significantly younger, suggesting that lifestyle and diet might contribute to early hair loss risk.
6 citations
,
September 2025 in “Cosmetics” This study introduced laser-assisted exosome delivery and observed early signs of clinical improvement in two patients, though causality cannot be inferred from these preliminary, uncontrolled cases.
5 citations
,
January 2020 in “International Journal of Trichology” This study found that both microneedling and microneedling with platelet-rich plasma improved hair thickness and density in male pattern alopecia, but no additional benefit was observed with the addition of platelet-rich plasma.
5 citations
,
January 2018 in “International Journal of Trichology” This study found no significant difference in the tensile properties of hair from different scalp positions, suggesting that microscopic structural heterogeneities may play a role.
4 citations
,
March 2024 in “Cells” This study found that the microRNAs oar-miR-23b and oar-miR-133 inhibit the proliferation and migration of sheep dermal fibroblasts, impacting the development of hair follicles in superfine wool sheep by targeting the genes TGFβ2 and NOTCH1.
3 citations
,
January 2023 in “Journal of Cutaneous and Aesthetic Surgery” Intradermal PRP significantly improved melasma in dark skin, with lasting results and no relapse after 3 months.
2 citations
,
June 2025 in “Cosmetics” This study observed that a five-week topical treatment with cold-pressed Rosa canina seed oil significantly reduced mean wrinkle scores and UV-induced spots in volunteers, suggesting potential anti-aging and photoprotective benefits attributed to its high carotenoid content.
2 citations
,
January 2025 in “Medicine” This study in Saudi female patients with hyperprolactinemia found that pituitary imaging is often indicated due to a high prevalence of pituitary anomalies, with prolactin levels showing moderate accuracy in predicting adenomas and a suggested cutoff level of >38.71 ng/mL for diagnosis.
2 citations
,
December 2024 in “International Journal of Molecular Sciences” This study found that mesenchymal stem cells from chronically inflamed human livers maintain their key cellular characteristics, supporting their potential use in developing liver cell therapies.
2 citations
,
December 2024 in “Neural Regeneration Research” This research review highlights the potential of exosome therapy to transform stroke treatment, reporting that in animal models, exosomes can reduce neuroinflammation, oxidative stress, and cell death, while promoting brain repair and regeneration. However, more evidence is needed before clinical applications in humans are established.
2 citations
,
October 2024 in “Pharmaceutics” This study found that reducing the particle size of Tetrastigma hemsleyanum powders improved both dissolution rates and antioxidant activity, suggesting potential benefits for enhancing hepatoprotective effects.
2 citations
,
February 2021 in “Case reports in dermatological medicine” In this case series, the topical botanical formulation GASHEE demonstrated significant improvements in hair regrowth without adverse events among patients with hair loss, including cases where previous treatments had failed.
1 citations
,
August 2025 in “Bioengineering” In this study, the combination of full-thickness skin column grafts and the TSN6 peptide improved wound healing quality in pigs by enhancing epidermal maturation compared to other treatments.
1 citations
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August 2024 in “Pharmaceuticals” This study found that goat placenta extract, when combined with PEGylated liposomes and microspicule gel, significantly promoted hair regrowth in patients experiencing hair loss due to chemotherapy by enhancing hair cell proliferation without causing skin irritation over a 12-week application period.
1 citations
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April 2024 in “Plastic & Reconstructive Surgery Global Open” This study found that using a blunt cannula for lip augmentation is a safe and effective alternative to traditional needle methods, resulting in no bruising and high patient satisfaction, which may influence future cosmetic practices.
1 citations
,
October 2022 in “Bioengineering” This study found that adding keratin to a collagen hydrogel improved keratinocyte differentiation compared to a pure collagen hydrogel, particularly when calcium was also present in the media.
1 citations
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July 2022 in “PLOS ONE” This study found that in Lichen Planopilaris, the Microbacteriaceae family was negatively correlated with IL-23 expression, suggesting a role in the disease's inflammation and microbiota composition.
1 citations
,
July 2022 in “Evidence-based Complementary and Alternative Medicine” This study found that high-flux hemodialysis combined with L-carnitine improved heart function, reduced inflammation, and decreased venous fistula complications in maintenance hemodialysis patients.
1 citations
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November 2021 in “Translational pediatrics” This meta-analysis reported no significant improvement in muscle strength or mobility with glucocorticoid treatment for progressive muscular dystrophy but observed an increase in adverse effects like acne and emotional irritability.
1 citations
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August 2018 in “Anais Brasileiros de Dermatologia” This study found that facial threading decreased skin roughness and improved subjective assessments of skin smoothness and color after three sessions.