Matrix Effects And Application Of Matrix Effect Factor

    November 2017 in “ Bioanalysis ”
    Wanlong Zhou, Shuang Yang, Perry G. Wang
    Studysummary This commentary discusses the challenges of matrix effects in LC–MS analysis and introduces the concept of a matrix effect factor using stable isotopically labeled internal standards to improve analysis reliability.
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    Research cited in this study 1

    1. Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations Analytical Chemistry · 1998