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This review highlights the promising potential of 3D printing for creating microneedles with precise customization and improved performance compared to traditional micromolding, emphasizing applications in personalized medical devices and advancements in biomedical fields.

This review discusses the potential role of Demodex mites in various human skin conditions, including acneiform eruptions and folliculitis, but reports no new research findings.

This study found that FLCN deficiency in mice muscles led to increased mitochondrial biogenesis and a metabolic shift towards oxidative phosphorylation, with a similar advantage observed in FLCN-null kidney cancer cells.

This study reported that once-daily treatment with oral minoxidil and spironolactone for 12 months reduced hair loss severity and hair shedding in women with pattern hair loss, with generally mild side effects, though results came from an uncontrolled, observational pilot study.

This study found that type II keratins in proliferating epithelial tissues are phosphorylated at a conserved motif during mitosis and stress, impacting keratin solubilization and reorganization.

This study identified a novel heterozygous missense mutation in the hHb3 gene associated with monilethrix, highlighting its role in this hair disorder.

A specific gene mutation causes woolly hair and hair loss.

This study found that 1% minoxidil topical solution led to terminal hair regrowth in some patients with alopecia areata, though it was only cosmetically acceptable in less than half of those cases.

This study developed minoxidil sulphate-loaded chitosan nanoparticles that doubled drug delivery to hair follicles in vitro compared to a control solution, suggesting potential for improved alopecia treatment.

This review summarizes recent progress in microneedle-based drug delivery systems and discusses their potential impact on cellular mechanisms and immunization signaling pathways, highlighting the need for further development in fabrication methods.

This study demonstrated that dominant mutations in mouse gasdermin A3 disrupt mitochondrial oxidative stress regulation, suggesting a gain-of-function effect on epidermal differentiation.

This study found that treating mtDNA mutator mice with the antioxidant SkQ1 delayed aging traits and extended their lifespan, potentially by alleviating mitochondrial dysfunction caused by reactive oxygen species.

In this study, EDA-A2 transgenic mice exhibited multifocal myodegeneration dependent on XEDAR, suggesting a potential role for XEDAR in skeletal muscle homeostasis.

This study found that topically applied minoxidil was more effective than nitroglycerin and placebo in enhancing penile diameter, rigidity, and arterial flow, with the most pronounced effects in patients with neurogenic impotence.

In this study, researchers found that depleting mtDNA in mice caused skin wrinkles and hair loss but restoring mitochondrial function reversed these effects, highlighting mtDNA's significant role in skin and hair health.

This study found that hair follicles are a significant and efficient pathway for the absorption of topical minoxidil foam in humans, with faster blood detection when follicles are open.

In this study, application of salicylic acid solution on mouse skin showed histologic changes without causing wounds or inflammation, observed immediately and up to 48 hours after treatment.

This review explores the hair follicle microbiome's interaction with the immune system, discussing its potential clinical implications for scalp health and disease but reports no new clinical results.

This study identified that a deficiency in the palmitoyl transferase enzyme, due to a mutation in the Zdhhc13 gene, led to severe physiological abnormalities in mice, including skin, bone, and systemic amyloid issues.

Minoxidil can cause excessive hair growth.

This review provides a comprehensive guide to the human microbiome and reports no new experimental results; it highlights the impact of modern lifestyles on microbial homeostasis and the necessity of conservation efforts.

Minoxidil helps hair cells live longer and grow longer.

This study found that mice with a specific loss of DNA methyltransferase 1 showed uneven epidermal thickness, reduced hair regeneration, and progressive alopecia, emphasizing DNA methylation's role in stem cell homeostasis.

This study found that epidermal growth factor treatment in male mice delayed normal skin development, inhibiting hair growth and follicle development by maintaining birth-level cell proliferation and differentiation for several days.

This study proposes the miR-22-5p-LEF1 axis as a novel pathway that may regulate hair follicle stem cell proliferation.

This study presents a novel in vitro assay using human folliculoid microspheres to research hair growth, which may facilitate preclinical testing of hair growth-modulatory agents.

This study found that oral finasteride was more effective than 5% topical minoxidil in treating mild to severe androgenetic alopecia in males, with both treatments deemed effective and safe over 12 months.

This review highlights the challenges of using hair mineral analyses as precise indicators of mineral status due to various influencing factors, suggesting they may be informative when combined with other indicators.

This article reviews the role of microRNAs in skin-related conditions like psoriasis and wound healing and highlights their potential as therapeutic targets and diagnostic biomarkers, without reporting new experimental results.

Minoxidil treatment increased hair growth for up to 5 years, requiring twice daily application.