Minoxidil: Hope for the Bald?

May 1987 in “ The Lancet ”

AntonC. De Groot, JohanP. Nater, Andrew Herxheimer

minoxidil androgenic alopecia male pattern baldness Rogaine

Studysummary Minoxidil helps some bald men, but most lose hair again when stopping.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

27 / 27 results

research Diseases of the Hair and Scalp

189 citations , May 1991 in “Medical Entomology and Zoology”

This abstract lists chapters on various hair and scalp conditions and treatments but reports no new research findings.

research Long-Term Follow-Up of Men with Male Pattern Baldness Treated with Topical Minoxidil

51 citations , March 1987 in “Journal of The American Academy of Dermatology”

This study found that twice-daily application of 3% topical minoxidil maintained a higher nonvellus hair count compared to once-daily application over 2 years and 9 months in men with male pattern baldness.

research Topical Minoxidil Does Not Act as an Antiandrogen in the Flank Organ of the Golden Syrian Hamster

26 citations , January 1987 in “Archives of Dermatology”

In this study, topical minoxidil did not show an antiandrogenic effect on androgen-dependent cutaneous structures in the golden Syrian hamster, suggesting it likely does not have this role in humans either.

research Topical Minoxidil: Efficacy and Cost-Effectiveness in Hair Loss Treatment

7 citations , January 1987 in “Archives of Dermatology”

This study reports that over 70% of responding dermatologists prescribed topical minoxidil, but a small percentage accounted for most prescriptions and few reported complications beyond local irritation.

research Dose-Response Study of Topical Minoxidil in Male Pattern Baldness

58 citations , July 1986 in “Journal of The American Academy of Dermatology”

Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.

research Topical Minoxidil Dose-Response Effect in Alopecia Areata

54 citations , February 1986 in “Archives of Dermatology”

This study found that 5% topical minoxidil solution led to greater hair regrowth in severe alopecia areata patients compared to 1% minoxidil, although most regrowth was not cosmetically acceptable.

research A Trial of 1% Minoxidil Used Topically for Severe Alopecia Areata

27 citations , January 1986 in “PubMed”

This study found no significant difference in hair growth between patients with extensive alopecia areata treated with 1% minoxidil and those given a placebo.

research Topical Minoxidil Useful in 18% of Patients with Androgenetic Alopecia: A Study of 430 Cases

16 citations , January 1986 in “Dermatology”

In this study, 1% minoxidil lotion led to good results in 18% of male patients with androgenetic alopecia, but only 6% maintained regrowth one year after stopping treatment.

research Scalp Comedones After Topical Minoxidil

19 citations , December 1985 in “Journal of The American Academy of Dermatology”

Minoxidil can cause scalp comedones and acne.

research Contact Dermatitis to Minoxidil

34 citations , September 1985 in “Contact Dermatitis”

Minoxidil can cause skin irritation like eczema and rash in some users.

research Topical Minoxidil in Early Male Pattern Baldness

138 citations , August 1985 in “Journal of The American Academy of Dermatology”

Minoxidil promotes hair growth in male pattern baldness.

research Allergic Contact Dermatitis to Minoxidil

29 citations , August 1985 in “Contact Dermatitis”

Minoxidil can cause allergic reactions like burning, itching, and red bumps.

research Pemphigus Vulgaris in Only One of Two Monozygotic Twins

20 citations , March 1985 in “Journal of The American Academy of Dermatology”

Genetic factors alone might not cause pemphigus vulgaris; other factors like birth complications and puberty may trigger it.

research Topically Applied Minoxidil in Baldness

26 citations , March 1985 in “International Journal of Dermatology”

Minoxidil helps hair growth, but results vary.

research Topical Minoxidil Reduces Blood Pressure

17 citations , March 1985 in “Journal of The American Academy of Dermatology”

Minoxidil can lower blood pressure in some people.

research Topical Minoxidil Therapy in Hereditary Androgenetic Alopecia

55 citations , February 1985 in “Archives of Dermatology”

In this randomized trial, topical minoxidil treatment resulted in cosmetically acceptable hair growth in 32% of men with hereditary male pattern baldness, with no serious side effects reported.

research Percutaneous Absorption of Minoxidil in Humans

52 citations , February 1985 in “Archives of Dermatology”

Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.

research Topical Minoxidil for Hair Regrowth

80 citations , September 1984 in “Journal of The American Academy of Dermatology”

In this study, 5% topical minoxidil was observed to promote hair regrowth in some patients with androgenic alopecia, while no regrowth was noted in patients with alopecia areata.

Minoxidil Stimulates Cutaneous Blood Flow in Human Balding Scalps: Pharmacodynamics Measured by Laser Doppler Velocimetry and Photopulse Plethysmography

research Minoxidil Stimulates Cutaneous Blood Flow in Human Balding Scalps: Pharmacodynamics Measured by Laser Doppler Velocimetry and Photopulse Plethysmography

137 citations , May 1984 in “Journal of Investigative Dermatology”

Minoxidil increases blood flow in balding scalps, possibly reversing hair loss.

research Alopecia Areata Treated With Topical Minoxidil

78 citations , April 1984 in “Archives of Dermatology”

This study found that 1% minoxidil topical solution led to terminal hair regrowth in some patients with alopecia areata, though it was only cosmetically acceptable in less than half of those cases.

research Direct Effects of Minoxidil on Epidermal Cells in Culture

63 citations , January 1984 in “Journal of Investigative Dermatology”

Minoxidil promotes hair growth by increasing cell division and DNA synthesis.

research Effect of Minoxidil on Cultured Keratinocytes

72 citations , December 1983 in “Journal of Investigative Dermatology”

Minoxidil helps hair cells live longer and grow longer.

research Topical Minoxidil in the Treatment of Alopecia Areata

80 citations , October 1983 in “BMJ”

This study found that 1% topical minoxidil induced significant hair regrowth in patients with alopecia areata, though it was less effective for those with extensive hair loss such as alopecia totalis and universalis.

research Lack of a Gonadal or Adrenal Androgenic Mechanism for the Hypertrichosis Produced by Diazoxide, Phenytoin, and Minoxidil

24 citations , May 1982 in “Biochemical Pharmacology”

These drugs cause hair growth without affecting testosterone or adrenal hormones.

research Reversal of Baldness in Patient Receiving Minoxidil for Hypertension

95 citations , December 1980 in “The New England Journal of Medicine”

Minoxidil helped bald patient regrow hair.

research Hypertrichosis Due to Minoxidil

45 citations , November 1979 in “British Journal of Dermatology”

This report describes a case of hypertrichosis associated with minoxidil use and suggests that nearly all patients on this drug may experience this side effect.

research Minoxidil-Induced Hypertrichosis: Treatment with Calcium Thioglycolate Depilatory

26 citations , April 1977 in “PubMed”

This report notes that five women experiencing hypertrichosis as a side effect of minoxidil had successful hair removal using a calcium thioglycolate depilatory agent.