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    Glossary MHC Class I Polypeptide-Related Sequence B

    plays a role in immune response by signaling stressed cells

    MHC Class I Polypeptide-Related Sequence B, also known as MICB, is a protein that plays a role in the immune system. It is part of the MHC (Major Histocompatibility Complex) class I family and is involved in the recognition and destruction of infected or cancerous cells by natural killer (NK) cells and certain T cells. This protein is important for the body's ability to detect and respond to cellular stress.

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    1. MHC Class I-Like MILL Molecules Are β2-Microglobulin-Associated, GPI-Anchored Glycoproteins That Do Not Require TAP for Cell Surface Expression The Journal of Immunology · 2006 · 16 citations
    2. Construction of regulatory network for alopecia areata progression and identification of immune monitoring genes based on multiple machine-learning algorithms Precision clinical medicine · 2023 · 3 citations
    3. Dandruff lesional scalp skin exhibits epidermal T cell infiltration and a weakened hair follicle immune privilege International Journal of Cosmetic Science · 2024
    4. Cell Surface B2m-Free Human Leukocyte Antigen (HLA) Monomers and Dimers: Are They Neo-HLA Class and Proto-HLA? Biomolecules · 2023 · 3 citations
    5. Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats PLoS ONE · 2016 · 127 citations
    6. Biliary fibrosis is an important but neglected pathological feature in hepatobiliary disorders: from molecular mechanisms to clinical implications Medical Review · 2024 · 6 citations
    7. Bioinformatic analysis of gene expression data reveals Src family protein tyrosine kinases as key players in androgenetic alopecia Frontiers in Medicine · 2023
    8. The JAK/STAT signaling pathway: from bench to clinic Signal Transduction and Targeted Therapy · 2021 · 489 citations
    9. Intramembrane Proteolysis of Astrotactins Journal of Biological Chemistry · 2017 · 8 citations
    10. AIRE Deficiency Leads to the Development of Alopecia Areata‒Like Lesions in Mice 2022 · 2 citations
    11. Precision therapeutics in non-scarring alopecia: a systemic genomic and pathway-based framework for targeted interventions ADMET & DMPK · 2025
    12. INTERFERONS IN DERMATOLOGY Dermatologic Clinics · 1998 · 22 citations
    13. Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases Trends in Molecular Medicine · 2018 · 80 citations
    14. Impacto del desequilibrio del microbioma del cuero cabelludo en la severidad de la alopecia areata, marcadores inflamatorios y cambios post-tratamiento Universidad de Córdoba Insitutional Repository (Universidad de Córdoba) · 2025
    15. All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration Stem cell biology and regenerative medicine · 2018
    16. Alopecia Areata The New England Journal of Medicine · 2012 · 421 citations
    17. Abstracts Journal of Investigative Dermatology Symposium Proceedings · 2003
    18. Fractional Laser-assisted Hair Regrowth and Microneedling for the Treatment of Alopecia Areata: A Review Cureus · 2019 · 7 citations
    19. Cutaneous signals of immune system disease Current problems in dermatology · 1991
    20. What is behind the ‘swarm of bees’ in alopecia areata British Journal of Dermatology · 2018 · 7 citations
    21. Clinical perspectives on the age-related increase of immunosuppressive activity Journal of Molecular Medicine · 2022 · 55 citations
    22. From mechanisms to therapies: current advances breakthroughs in alopecia areata immunopathology Frontiers in Immunology · 2025 · 3 citations
    23. British Association of Dermatologists living guideline for managing people with alopecia areata 2024 British Journal of Dermatology · 2024 · 20 citations
    24. British Association of Dermatologists living guideline for managing people with alopecia areata 2025 British Journal of Dermatology · 2025
    25. Cellular and Molecular Mechanisms of Wound Repair: From Biology to Therapeutic Innovation Cells · 2025 · 5 citations
    26. Alopecia Areata: Burden of Disease, Approach to Treatment, and Current Unmet Needs Clinical, Cosmetic and Investigational Dermatology · 2023 · 1 citations
    27. Immunological aspects and gender bias during respiratory viral infections including novel Coronavirus disease‐19 (COVID‐19): A scoping review Journal of Medical Virology · 2021 · 11 citations
    28. Systemic humoral activation facilitates tissue regeneration by D-chiral biomaterial scaffolds Cell Biomaterials · 2026
    29. SIRT1 downregulation provokes immune-inflammatory responses in hair follicle outer root sheath cells and may contribute to development of alopecia areata Journal of Dermatological Science · 2023 · 13 citations
    30. Commonly associated disorders with complete scalp alopecia in early childhood: A review International journal of trichology · 2023