June 2026 in “International Journal of Advanced Multidisciplinary Research and Studies” This study highlights the potential of a ketoconazole antifungal hair spray as an innovative and effective topical method for treating tinea capitis, offering benefits such as easy application, improved drug penetration, and reduced systemic exposure compared to conventional treatments.
November 2016 in “The Molecular Biology Society of Japan” January 2022 in “Wiadomości lekarskie (Warsaw Poland)” This study found that Methylsulfonylmethane significantly reduced hair loss and enhanced hair growth and follicle number in male mice, attributed to its antioxidant and anti-inflammatory properties.
November 2025 in “JOURNAL OF EXPERIMENTAL ZOOLOGY INDIA” This study observed that thymol from Origanum marjoram essential oil significantly promoted hair regrowth and reduced inflammation in cyclophosphamide-induced alopecia in rabbits, with effects that were comparable to or exceeded those of betamethasone, highlighting its potential as a safer treatment alternative.
In this in-vitro study, neem leaf extract, combined with oils from Eucalyptus citriodora and Cymbopogon martini, inhibited dermatophyte growth responsible for tinea capitis, showing potential for developing a treatment formulation against the infection.
1 citations
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June 1999 in “American Journal of Contact Dermatitis” This review discusses the choice and formulation of medicated and cosmetic shampoos for scalp disorders and hair aesthetics, providing guidelines based on hair types and patient age, and reports no new results.
3 citations
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January 2018 in “Food Science and Technology Research” This study found that 6-methylsulfinylhexyl isothiocyanate (6-MSITC) significantly promoted proliferation and upregulated specific mRNA levels in human dermal papilla cells, suggesting potential as a hair growth stimulant.
1 citations
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November 2004 in “International Journal of Cosmetic Science” In this study, synchrotron-powered infrared microscopy revealed that hair follicles are a favored penetration pathway for cyanophenol and ethylhexyl methoxycinnamate in human skin, without altering protein secondary structure.
December 2025 in “Pharmaceuticals” This study found that a natural illite-based carrier could deliver minoxidil topically with preserved efficacy, minimizing solvent toxicity, and showed hair-growth-promoting activity via anti-inflammatory and pro-proliferative mechanisms in mice.
November 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that combining 7% chamomile extract with 5% minoxidil solution may reduce cutaneous side effects like itching, scaling, and erythema in male patients with androgenic alopecia, potentially improving treatment compliance.
May 2026 in “Advanced Materials Interfaces” This study reported that a new coating made with delaminated Ti₃C₂ MXene nano-sheets and a tea-derived compound effectively protects hair keratin from damage by providing UV screening, thermal dissipation, and antioxidation, while also enhancing mechanical strength and restoring wettability.
38 citations
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June 2005 in “Contact Dermatitis” This case report describes a patient with an allergic sensitization to minoxidil, indicating that such patients should pursue alternative therapies to treat androgenetic alopecia.
9 citations
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January 2006 in “Cutaneous and ocular toxicology” This study found that L-cystine, D-pantothenat, and miliacin can enhance the metabolic capacity and proliferation of human keratinocytes, with a combination of these additives potentially providing synergistic benefits in growth media.
January 2022 in “Food Science and Technology” This study suggests that a mixture of Chrysanthemum zawadskii, peppermint, and Glycyrrhiza glabra promotes hair growth and reduces hair loss markers in testosterone-treated cells and mice.
5 citations
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February 2017 in “Biomolecules & Therapeutics” The authors reported that 4-O-methylhonokiol decreased TGF-β1-induced cell cycle arrest and oxidative stress markers in human keratinocyte cells, suggesting a potential protective role in TGF-β1-mediated cell cycle regulation.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated the effectiveness of three formulated hair conditioners—Herbal, Synthetic, and Ayurvedic—using organoleptic and physicochemical tests like pH, Dirt Dispersion, and Stability, with the main aim to develop a product that meets user compliance and desired hair care effects.
1 citations
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January 1997 in “Skin research” Hinokitiol and pantothenylethylether in hair products can cause strong allergic reactions.
August 2021 in “Majalah Obat Tradisional” This study found that a hair tonic formulated from green tea extract showed similar hair growth-promoting activity to 2% Minoxidil in rabbits, without causing skin irritation or bacterial contamination.
14 citations
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September 2021 in “International journal of molecular sciences” This review details how zinc pyrithione's anti-fungal activity makes it a successful treatment for dandruff and seborrheic dermatitis, by effectively targeting Malassezia yeast in the scalp.
December 2022 in “Research journal of topical and cosmetic sciences” This study evaluated a herbal anti-dandruff hair wash powder, TRICHONEMTM, composed of eighteen herbal ingredients, reporting effective in vitro anti-dandruff activity and high user satisfaction in a 4-week pilot trial involving 50 women, without causing irritation.
May 2021 in “Boletín latinoamericano y del Caribe de plantas medicinales y aromáticas” This study found that ethanolic extracts of Microsechium helleri showed notable antioxidant, hypoglycemic, and cardioprotective activities, while chloroformic extracts exhibited significant anti-inflammatory effects in experimental models.
44 citations
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March 2016 in “Frontiers in cellular neuroscience” In this study using zebrafish, four bisbenzylisoquinoline derivatives were found to protect hair cells from aminoglycoside-induced damage without reducing antibiotic efficacy, potentially leading to therapies for patients undergoing such treatments.
In this study, researchers assessed the physical-chemical and microbiological stability of various pharmaceutical ingredients in the vehicle TrichoSolTM, finding differing beyond-use dates for the compounds, such as 180 days for cetirizine hydrochloride, but only 90 days for progesterone at higher concentrations.
May 2026 in “International Journal of Zoology and Applied Biosciences” This study developed and tested an herbal shampoo powder using medicinal plants, finding that formulation F6—which includes Tulsi and Neem—showed the highest antimicrobial efficacy against Pityrosporum ovale and Escherichia coli, with the formulations remaining non-irritant to skin and providing a stable alternative to synthetic shampoos.
4 citations
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September 2011 in “American Journal of Clinical Dermatology” This case series suggests that EE/CMA 0.03mg/2mg may help manage dermatological disorders related to androgen excess, as evidenced by symptomatic improvements in the four patients treated.
September 2018 in “Reactions Weekly” Two women had skin reactions from a hair loss treatment and got better after stopping use.
December 2023 in “Pharmaceutics” In this study, nanoparticles developed with Minoxidil-loaded thiolated β-CDs showed promise for topical scalp use, as they significantly improved drug retention on hair and displayed no irritation in rabbits.
5 citations
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July 2019 in “Photodiagnosis and photodynamic therapy” This study reports a case of a 59-year-old female with refractory follicular mucinosis and diffuse scalp alopecia who achieved complete clinical remission following treatment with a combination of topical tacalcitol and photodynamic therapy.
September 2024 in “Journal of Anatomy and Histopathology” In this study, researchers found that topical application of 3-β-methoxy-Δ18-oleanene (miliacin) in mice sped up the recovery of hair follicles damaged by cyclophosphamide, moving them into a new hair growth cycle more quickly compared to controls.
January 2005 in “Seibutsu Butsuri/Seibutsu butsuri” Chemical treatments damage hair more than UV exposure, making it thinner and less flexible.