research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
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research Cancer Risk in Polycystic Ovary Syndrome Patients: Common Treatments and Future Perspectives
PCOS may increase the risk of certain cancers.
research Calcium Regulation of Stem Cells
Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
research A Long-Term Follow-Up Study of Men Born with Very Low Birth Weight and Their Reproductive Hormone Profile
Men born very underweight had higher estrogen levels but normal reproduction compared to normal birth weight men.
research Fibrous Scaffolds Potentiate the Paracrine Function of Mesenchymal Stem Cells: A New Dimension in Cell-Material Interaction
Special fiber materials boost the healing properties of certain stem cells.
research Serum Lipid Profile and Insulin Resistance in Women with Polycystic Ovary Syndrome
Women with PCOS may have higher bad cholesterol and are at risk for blood sugar issues; lifestyle changes are recommended.
research Type 2 Diabetes, Metabolic Syndrome, and Lipid Metabolism
Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.
research Analysis of Isotretinoin-Induced Alterations in the Levels of Plasma Trace Elements: Investigation of the Relationship Between Magnesium, Phosphorus, Potassium, Zinc, and Treatment-Related Side Effects
Isotretinoin affects trace element levels and requires monitoring of liver and kidney functions.
research Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
research The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches
Fat cells are important for tissue repair and stem cell support in various body parts.
research Circulating Testosterone and Feather-Gene Expression of Receptors and Metabolic Enzymes in Relation to Melanin-Based Coloration in the Barn Owl
Barn owls with smaller black spots have higher testosterone levels, which might be due to genetic effects on hormone regulation rather than hormone effects on coloration.
research What Does the Concept of the Stem Cell Niche Really Mean Today?
Stem cell niches support, regulate, and coordinate stem cell functions.
research Friends Turned Foes: Angiogenic Growth Factors Beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Fibronectin Connecting Cell Sheet Based on Click Chemistry for Wound Repair
Fibronectin-attached cell sheets improve wound healing and are safe and effective.
research Effect of an Oral Probiotic Formula on Scalp and Facial Skin Condition, Glucose, and Lipid Metabolism
Taking a probiotic supplement twice a day improved hair growth, skin hydration, and metabolic health in adults at risk of metabolic syndrome.
research Frizzled Receptors in Development and Disease
Frizzled receptors are essential for various body development processes and maintaining certain body functions.
research Simultaneous LC-MS/MS Quantification of Glucocorticoids, Melatonin, and Its Metabolites in Hair
The new method can measure sleep-related hormones in hair effectively and could help track long-term sleep patterns.
research Inherited Disorders of Corneocyte Proteins
Ichthyoses are genetic skin disorders that affect the skin's barrier function.
research Novel Insights Into the Molecular Mechanisms Underlying Generalized Glucocorticoid Resistance and Hypersensitivity Syndromes
Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
research Biological Activities of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside in Antiaging and Antiaging-Related Disease Treatments
THSG from a Chinese plant helps with aging and related diseases.
research Bioengineering Skin Constructs
Future research should focus on making bioengineered skin that completely restores all skin functions.
research Testosterone Replacement in 49,XXXXY Syndrome: Andrological, Metabolic, and Neurological Aspects
Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.
research The Menopausal Transition: Is the Hair Follicle Going Through Menopause?
Menopause can cause hair thinning and texture changes due to hormonal and metabolic shifts.
research Collagen Involvement in Health, Disease, and Medicine
Collagen is crucial for health and treating certain diseases, and supplements can improve skin, nails, and hair conditions.
research Comparing the Efficacy of Myo-Inositol Plus Alpha-Lactalbumin Versus Myo-Inositol Alone on Reproductive and Metabolic Disturbances of Polycystic Ovary Syndrome
Myo-inositol plus α-lactalbumin works better than myo-inositol alone for improving symptoms of PCOS.
research Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications
Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.
research Circadian Clocks: From Stem Cells to Tissue Homeostasis and Regeneration
Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
research Systemic Subchronic Toxicity and Comparison of Four Selenium Nutritional Supplements by 90-Day Oral Exposure in Sprague-Dawley Rats
High doses of some selenium supplements caused liver and reproductive harm in rats.
research Association of Lifelong Intake of Barley Diet with Healthy Aging: Changes in Physical and Cognitive Functions and Intestinal Microbiome in Senescence-Accelerated Mouse-Prone 8 (SAMP8)
Eating barley for life may lead to healthier aging in mice.
research Trace Element Zinc and Skin Disorders
Zinc is important for skin health, and supplements can help treat various skin and hair disorders, but more research is needed for conditions like psoriasis and vitiligo.