15 citations,
September 1999 in “British Journal of Dermatology” Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.
25 citations,
November 2018 in “Cell reports” The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
8 citations,
March 2014 in “American Journal of Pathology” Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.
26 citations,
December 2017 in “Journal of Investigative Dermatology” Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.
131 citations,
July 2009 in “Experimental Dermatology” The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
30 citations,
June 1993 in “The Journal of Cell Biology” The oncoprotein causes abnormal hair growth without increasing skin cancer risk.
62 citations,
July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
9 citations,
August 2005 in “Experimental Dermatology” Modified pep7, named EPM peptide, effectively promotes hair growth at low concentrations and works well with minoxidil.
1 citations,
January 2017 in “Elsevier eBooks” The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.
33 citations,
January 1997 in “Endocrinology” Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.
17 citations,
January 1997 in “Cell and Tissue Research” Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.
10 citations,
July 2011 in “Wound Repair and Regeneration” New antiscarring strategies show promise, including drugs, stem cells, and improved surgical techniques.
1 citations,
July 2023 in “Communications biology” Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
19 citations,
January 1997 in “Endocrinology” Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.
April 2024 in “Biomolecules” Exosomal miRNAs from stem cells can help improve skin health and delay aging.
Glycyrrhizic acid and licorice extract can significantly reduce unwanted hair growth.
2 citations,
November 2019 in “Cancer reports” The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.
July 2023 in “Bioengineering & translational medicine” Mesenchymal stem cell proteins in a special gel improved healing of severe burns.
May 2023 in “Cytotherapy” Hair follicle and adipose cell vesicles both protect neurons and reduce inflammation similarly.
22 citations,
April 2022 in “Stem cell research & therapy” Hair follicle-derived extracellular vesicles may help heal chronic wounds as effectively as those from adipose tissue.
11 citations,
December 2018 in “Bone” Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
11 citations,
February 2019 in “Stem cells international” Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
8 citations,
June 2022 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.
1 citations,
November 2023 in “Biomaterials advances” Sponges made of soy protein and β-chitin with human cells from hair or fat can speed up healing of chronic wounds.
April 2024 in “Research Square (Research Square)” MSC-protein helps regenerate gum tissue and bone.
September 2017 in “Journal of Investigative Dermatology” BMPs are crucial for hair growth and their decrease by androgens leads to hair loss.
Bone Morphogenetic Proteins (BMPs) are important for hair growth, and their decrease due to hormones could lead to hair loss, but adding more BMPs could promote hair growth.
8 citations,
February 2014 in “Stem cells translational medicine” Modified stem cells that overexpress a specific protein can improve hair growth and reduce hair abnormalities in mice.
46 citations,
July 2015 in “Wound repair and regeneration” Keloid scars may form due to changes in skin cell characteristics and specific protein signaling.
300 citations,
August 2012 in “Seminars in Cell & Developmental Biology” The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.