Clinical Efficacy and Safety of Kanglaite Injection, Adjuvant Gemcitabine and Cisplatin Chemotherapy for Advanced Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis
December 2021
in “
Tropical Journal of Pharmaceutical Research
”
TLDR Kanglaite injection with chemotherapy improves treatment and reduces side effects for advanced lung cancer.
The study investigated the effectiveness and safety of combining Kanglaite injection (KLTi) with gemcitabine and cisplatin (GP) chemotherapy for advanced non-small cell lung cancer (NSCLC). A meta-analysis of 25 randomized controlled trials revealed that KLTi plus GP chemotherapy significantly improved the objective response rate and disease control rate compared to GP chemotherapy alone. Additionally, it reduced adverse drug reactions, including hair loss, gastrointestinal reactions, liver and kidney impairment, nervous system damage, myelosuppression, anemia, leukopenia, thrombocytopenia, and hypochromia. The findings suggested that KLTi could be an effective and safe intervention for patients with advanced NSCLC.
