Search
for
Sort by
Research
300-330 / 1000+ results
research Smart Microneedles for Therapy and Diagnosis
This review discusses the design, properties, and potential applications of smart microneedles, with no new clinical results presented.
research Ultrasound-Activated GelMA Hydrogel Loaded with MSC-EVs Promotes Functional Regeneration of Skin Vasculature, Nerves, and Appendages
This study found that combining ultrasound with a GelMA hydrogel able to deliver mesenchymal stem cell-derived vesicles significantly improved wound healing in a mouse model by enhancing fibroblast activity, promoting re-epithelialization, and facilitating hair follicle regeneration, highlighting a novel approach to skin regeneration therapy.
research In vitro interactions between sensory nerves, epidermis, hair follicles and capillaries in a tissue‐engineered reconstructed skin
This study developed a tissue-engineered model of innervated skin, allowing for examination of how epidermis and capillaries affect nerve growth and offering a tool for further research on skin-related processes.
research Repeatable Perming via Thiol–Michael Click Reaction: Using Amide Derived from Maleic Acid and Cystine
In this study, the novel thiol-Michael click perming molecule, MA2-CySS, achieved repeatable perming with reduced oxidative damage, preserving hair keratin's structure while maintaining efficiency comparable to traditional oxidative methods.
research Biomimetic nanozymes for tumor diagnosis and treatment
This review examines nanozymes as promising tools for cancer diagnosis and therapy due to their enzyme-mimicking catalytic properties and highlights their challenges, including biosafety and clinical translation, alongside potential improvements through biomimetic designs, particularly utilizing exosome-based strategies for targeted delivery to tumors.
research Advances and applications of biomimetic biomaterials for endogenous skin regeneration
This review outlines recent advancements in biomimetic materials for skin regeneration, emphasizing their potential to mimic tissue structures and regulate physiological processes, and discusses future directions involving novel technologies like artificial intelligence and in situ reprogramming.
research Body temperature-responsive Janus patches accelerate diabetic wound regeneration via coupling mechanical transduction and biochemical pathways
research Rare Earth Elements: therapeutic and diagnostic applications in modern medicine
Rare earth elements are crucial in medical imaging and cancer treatment.
research Mouse Hair Cycle Expression Dynamics Modeled as Coupled Mesenchymal and Epithelial Oscillators
In this study, researchers found that synchronization between expanding epithelial cells and background mesenchymal cells in the mouse hair cycle may be maintained by inhibitory regulation, with potential mediators of this regulation identified.
research CLED: A Calcium-Linked Protein Associated with Early Epithelial Differentiation
research Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation
This study found that Msx2-deficient mice exhibit skull and bone formation defects similar to those seen in human MSX2-related conditions, highlighting the gene's importance in skeletal and organ development.
research Mouse Epidermal Neural Crest Stem Cell (EPI-NCSC) Cultures
This article details a protocol for isolating and culturing embryonic neural crest stem cells from the whisker follicles of adult mice.
research Changes in the proteomic profile of adipose tissue-derived mesenchymal stem cells during passages
This study suggests that common proteomic changes, including the expression of the protein S100A6, may occur during the expansion of AD-MSC from different donors.
research 10.1063/5.0132123.1
This study demonstrated that a single multimode fiber can be used for single-shot wide-field reflectance imaging, achieving high correlation with the ground truth and enabling real-time microendoscopy at up to 180 frames per second.
research N‑K GM SERIES: THE COMPLETE GEOMETRIC MEDICINE LIBRARY — From Discovery to Deployment: SELECTIVE‑ANTI‑BACTERIAL‑GM2, SELECTIVE‑ANTI‑PATHOGENIC‑FUNGI‑GM2, and the CMC Pocket Delivery System A Comprehensive Framework for Precision Antimicrobials — 1,000,000,000:1 Selectivity, Zero Ecological Harm, Free for Humanity
This publication presents a library of precision geometric medicines that reportedly kill harmful bacteria and fungi while sparing beneficial organisms, using a delivery system that targets pathogens specifically and avoids ecological harm.
research A quantitative technique to analyze and evaluate microstructures of skin hair follicles based on mueller matrix polarimetry
This study found that Mueller Matrix microscopy can accurately identify, detect, and evaluate hair follicles in mouse skin tissue, suggesting its potential for skin structure research and dermatological applications.
research N‑K GM SERIES: THE COMPLETE GEOMETRIC MEDICINE LIBRARY — From Discovery to Deployment: SELECTIVE‑ANTI‑BACTERIAL‑GM2, SELECTIVE‑ANTI‑PATHOGENIC‑FUNGI‑GM2, and the CMC Pocket Delivery System A Comprehensive Framework for Precision Antimicrobials — 1,000,000,000:1 Selectivity, Zero Ecological Harm, Free for Humanity
This publication presents a library of geometric medicines designed to selectively target pathogenic bacteria and fungi with high precision while minimizing ecological harm, available for free on a non-commercial basis.
research Dynamic immunomodulatory nanoarchitectonics: Rewiring tissue regenerative microenvironment via intelligent regulation
This article discusses how designing biomaterials to modulate immune responses has become a promising strategy for enhancing tissue repair and regeneration.
research Matrix effects and application of matrix effect factor
This commentary discusses the challenges of matrix effects in LC–MS analysis and introduces the concept of a matrix effect factor using stable isotopically labeled internal standards to improve analysis reliability.
research A Femtosecond Fiber Laser‐Based Compact Label‐Free Multimodality Nonlinear Optical Microscopy and Its Ex Vivo Bioimaging
This study introduced a novel microscopy system using an Er3 + −doped femtosecond fiber laser, achieving detailed imaging of biological structures in plant and skin samples with improved spatial resolution for various applications, including in vivo imaging.
research Mesenchymal stem cells and their secretome - candidates for safe and effective therapy for systemic lupus erythematosus
This review discusses the potential of mesenchymal stem cells and their secretome as promising therapeutic tools for systemic lupus erythematosus but reports no new clinical results.
research Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration
This review discusses the mechanisms and potential therapeutic benefits of mesenchymal stromal cell-derived extracellular vesicles delivered via biomaterials, but reports no new clinical results.
research Confocal Laser Scanning Microscopy as a Tool for the Investigation of Skin Drug Delivery Systems and Diagnosis of Skin Disorders
Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
research A Novel Ion – selective Polymeric Membrane Sensor for Determining Thallium(I) With High Selectivity
This study developed a sensor that effectively measures Tl+ cation in solutions with a wide dynamic range and low detection limit, responding linearly within the concentration range 1.0 × 10−8 to 1.0 × 10−1M.
research Analysis of Biological Elements of Scalp Hairs With Sem-Edx and Tem and its Application to the Hair Comparison
This study discusses using SEM/EDX for elemental analysis of hair samples in forensic science but notes challenges in detecting certain trace elements from raw hair.
research USING THE FROG EPIDERMIS TO UNCOVER DESMOSOME FUNCTION AND REGULATION IN THE DEVELOPING EMBRYO
In this study using Xenopus laevis embryos, reduced levels of the desmosomal protein desmoplakin led to defects in epidermal and cardiac structures, suggesting its crucial role in tissue integrity.
research De novo mutation in the mitochondrial tRNALeu(UUR) gene (A3243G) with rapid segregation resulting in MELAS in the offspring
This report documents a 14-year-old Chinese boy with mitochondrial encephalopathy, lactic acidosis, stroke-like episodes, and a de novo A3243G mitochondrial DNA mutation, highlighting the condition's multisystem involvement without ragged red fibers in muscle biopsy.
research Reverse engineering liver buds through self-driven condensation and organization towards medical application
research The Trilogy of Skin Regeneration via Metal-Organic Frameworks Nanomedicine: Precision Management of Refractory Wounds, Pathological Scarring, and Hair Follicle Reactivation
This review discusses metal-organic frameworks for treating diabetic infected wounds and related applications, reporting no new clinical results but highlighting challenges like biosafety and production for future research.