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Agomelatine might help reduce hair loss caused by valproate.

This review discusses the potential benefits of topical melatonin in aesthetic dermatology, including its antioxidant and protective properties for skin aging and photoaging, while also noting varying strengths of evidence across different skin conditions.

This review discusses the cutaneous serotoninergic/melatoninergic system's potential role in skin function and resilience against environmental and internal stresses, but does not report new experimental findings.

This study provides evidence that human skin contains genes and enzymes necessary for producing serotonin and melatonin.

This research found that melatonin plays a protective and modulatory role in skin biology, reducing UV damage and chemotherapy-induced hair follicle cell harm in human organ culture models.

This review discusses the protective and stress-buffering roles of melatonin in skin functions and structures but does not present new clinical findings.

This study reviews melatonin's diverse roles in dermatology, highlighting its potential to protect skin from UV damage and oxidative stress, enhance DNA repair, and influence hair follicle cycling, suggesting therapeutic applications in skin care and hair renewal.

This article discusses the potential role of melatonin in protecting skin against stress and maintaining homeostasis, based on its local synthesis and various protective functions, but presents no new clinical results.

This study suggests that melatonin plays a role in hair follicle function by modulating growth and pigmentation, and it may act as a protective agent in active hair growth phases.

This article discusses the role of neurohormones and neuropeptides in hair follicle pigmentation and outlines promising neuroendocrinological strategies to address greying and damage, but reports no new clinical results.

This study found that topical melatonin significantly improved hair density and reduced the severity of androgenetic alopecia in men and women.

This study suggests that melatonin enhances the growth properties of DP cells by activating the AKT/GSK3β/β-catenin signaling pathway through its receptors in a 3D culture system.

This study found that melatonin may enhance hair growth properties in dermal papilla cells by activating the AKT/GSK3β/β-catenin signaling pathway through melatonin receptors.

This study suggests that melatonin may promote hair growth properties by activating the AKT/GSK3β/β-catenin signaling pathway in dermal papilla cells.

This ex vivo study reported that melatonin significantly improved certain aging biomarkers in aged human skin, including reduced mTORC1 activity, increased fibrillin-1, and enhanced collagen and elastic fiber organization, though other key biomarkers remained unchanged.

This review summarizes recent findings on the combined use of chitosan and melatonin, highlighting their synergistic effects in wound healing, anti-cancer therapies, and tissue engineering, with further potential applications in cosmetology, aesthetic medicine, and veterinary practice.

This article discusses melatonin's roles in skin and hair growth, highlighting its antioxidative and anti-inflammatory properties, but reports no new clinical results.

This review discusses melatonin's potential in dermatology, highlighting its antioxidative, immunomodulatory, and DNA repair properties, but reports no new clinical results.

This review discusses the impact of melatonin and its metabolites on skin aging, summarizing how they may serve as "aging neutralizers" through their anti-oxidative and anti-inflammatory properties, but reports no new clinical results.

This review discusses the role of melatonin in skin and hair physiology, highlighting clinical evidence for its potential benefits in treating androgenetic alopecia, but does not report new results.

This source explores melatonin's roles beyond circadian rhythm regulation, reporting its benefits in skin conditions like dermatitis, melasma, alopecia, psoriasis, and skin aging due to its antioxidant, anti-inflammatory, and immunomodulatory properties, while highlighting the need for more trials on optimal dosing and long-term safety.

This review discusses the pathophysiology of sleep disturbance in children with atopic dermatitis and highlights the need for further research on management strategies, but provides no new clinical results.

This article reviews various studies and suggests that melatonin, produced both naturally in the skin and applied topically, may offer significant protection against environmental damage, making it a promising candidate for skincare therapies.

This review discusses the mechanism of action of melatonin in various disorders and suggests its potential for designing new receptor ligands, but reports no new clinical findings.

This review discusses the potential use of essential oils and melatonin as nutraceuticals in dogs, highlighting their promising applications for addressing conditions like stress, anxiety, sleep disorders, and alopecia.

This review explores the detrimental effects of sunlight on the skin’s circadian rhythm and photodamage, noting the potential of natural cosmeceuticals to influence this rhythm, but reports no new results.

In this animal study, AGO (agomelatine) effectively alleviated testosterone-induced benign prostatic hyperplasia in rats by reducing oxidative stress and inflammation, indicating its potential as a therapeutic option for managing BPH through specific signaling pathways.

This article reviews the generation of complex integument patterns through genetic, chemical, and environmental influences, with applications in tissue engineering, but reports no new experimental results.

This review updates the protective effects and molecular mechanisms of melatonin against ultraviolet-induced damage in human skin, reporting no new clinical findings.

This study found that 12 weeks of melatonin supplementation improved mental health and metabolic parameters in women with polycystic ovary syndrome compared to a placebo.