Peer Review of Melatonin Increases Growth Properties in Human Dermal Papilla Spheroids by Activating AKT/GSK3β/β-Catenin Signaling Pathway

The document is a peer review of a scientific paper titled "Melatonin increases growth properties in human dermal papilla spheroids by activating AKT/GSK3β/β-Catenin signaling pathway". The paper underwent two rounds of review. In the first round, the reviewers suggested major revisions, including clarifications in methodology, results, interpretation, and discussion. They also recommended improving the English language for better comprehension. In the second round, the reviewers acknowledged that the authors had adequately corrected and responded to their comments, leading to a significant improvement in the quality of the paper. The paper's main finding is that melatonin can enhance the growth properties of human dermal papilla spheroids, which are crucial for hair growth, by activating a specific signaling pathway.