Peer Review of 'Melatonin Increases Growth Properties in Human Dermal Papilla Spheroids by Activating AKT/GSK3β/β-Catenin Signaling Pathway'
May 2022
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Studysummary This study suggests that melatonin enhances the growth properties of DP cells by activating the AKT/GSK3β/β-catenin signaling pathway through its receptors in a 3D culture system.
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The document is a peer review of a scientific paper titled "Melatonin increases growth properties in human dermal papilla spheroids by activating AKT/GSK3β/β-Catenin signaling pathway". The paper explores the role of melatonin in hair growth. The reviewers initially had concerns about the clarity of the paper, the methodology used, and the interpretation of the results. However, after revisions, the reviewers found that the authors adequately addressed their comments and improved the quality of the paper. The reviewers also suggested that the authors consider the possibility of indirect action through melatonin metabolites and the relevance of skin cells producing melatonin. The paper was accepted after the revisions.
