learn Valproic acid
an anticonvulsant repurposed for hair loss via histone inhibition
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5 / 23 resultslearn Minoxidil
An essential vasodilator with some anti-androgenic effects, has excellent safety record
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learn KY19382
compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles
learn sh-Polypeptide-7
Research
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research Peer Review of Melatonin Increases Growth Properties in Human Dermal Papilla Spheroids by Activating AKT/GSK3β/β-Catenin Signaling Pathway
Melatonin improves hair growth-related cell properties by activating a certain cell signaling pathway.
research Peer Review of 'Melatonin Increases Growth Properties in Human Dermal Papilla Spheroids by Activating AKT/GSK3β/β-Catenin Signaling Pathway'
Melatonin may help hair growth by affecting certain cell signals, and the paper improved after revisions.
research Peer Review of 'Melatonin Increases Growth Properties in Human Dermal Papilla Spheroids by Activating AKT/GSK3β/β-Catenin Signaling Pathway'
Melatonin may improve hair growth by affecting certain cell signaling pathways.
research Melatonin Increases Growth Properties in Human Dermal Papilla Spheroids by Activating AKT/GSK3β/β-Catenin Signaling Pathway
Melatonin may help hair growth by affecting cell growth and hair-related signaling pathways.
research Wnt Activator CHIR99021-Stimulated Human Dermal Papilla Spheroids Contribute to Hair Follicle Formation and Production of Reconstituted Follicle-Enriched Human Skin
CHIR99021 helps create human skin with hair follicles, offering hope for hair loss treatments.
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5 / 1000+ resultscommunity Surprisingly thorough study on He-Shou-Wu/Fo Ti
He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.
community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community New and Interesting HairLoss Studies/Papers/Reviews
Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.
community The mechanism of androgenic alopecia
DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.
community Dht kills hair, but no one says why?
DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.