September 2022 in “Scientific Reports” This study found that scalp melanoma often occurs in areas with androgenetic alopecia, and patients without alopecia might experience a later diagnosis due to hair coverage, leading to potentially worse outcomes.
35 citations
,
January 1981 35 citations
,
August 2009 in “Journal of the American Academy of Dermatology” This study found a decreased number of follicular melanocytes in patients with alopecia areata, though it remains unclear if this decrease is due to autoimmune attack or rapid hair cycling.
15 citations
,
March 2015 in “Experimental Dermatology” Clotrimazole, an antifungal cream, may safely reduce skin pigmentation by breaking down the enzyme needed for making melanin.
66 citations
,
March 2019 in “Cellular and Molecular Life Sciences” This review discusses melanocyte development, emphasizing the plasticity of melanoblasts and the role of both intrinsic and extracellular signals in their differentiation and migration, with no new clinical results reported.
1 citations
,
November 2003 in “Annals of saudi medicine/Annals of Saudi medicine” This case report documents the first known instance of erythromelanosis follicularis faciei in a Saudi male, detailing its clinical and histopathological characteristics.
In this study, a two-year-old black Dobermann pinscher with progressive dorsal hair loss and folliculitis showed a partial response to prolonged omega-3/omega-6 fatty acid treatment.
This review discusses the factors influencing human hair color, including genetic components and enzymatic activity, and highlights the forensic significance of hair color analysis, but reports no new findings.
July 2023 in “International Journal of Trichology” In this case report, a 39-year-old man with sudden whitening of scalp hair due to alopecia areata experienced total regrowth of pigmented hair after six months without systemic treatment.
30 citations
,
January 2005 in “Elsevier eBooks” Vitamin D affects skin and hair by influencing cell behavior and melanin production.
10 citations
,
May 2016 in “Journal of Dermatological Science” This study found that PDGF-BB affects human melanocytes differently depending on their differentiation stage, stimulating melanoblast proliferation but inhibiting melanocyte proliferation while promoting their differentiation.
November 2022 in “Journal of Investigative Dermatology” This study found that the cytoplasmic dynein component Dynlt3 is essential for effective melanosome transport and transfer in mouse melanocytes, linking melanosome positioning and acidity to the Wnt/β-catenin signaling pathway.
This chapter reviews recent developments in vitiligo research, highlighting the role of melanocyte stem cell differentiation and oxidative stress in its management, but reports no new clinical results.
31 citations
,
May 2013 in “Clinical Cosmetic and Investigational Dermatology” This review discusses dermocosmetic care for managing DM-related dermatoses, reporting improved skin conditions and quality of life in patients, but highlights limited clinical evidence for these products.
6 citations
,
October 1998 in “PubMed” This case study reports a new variant of chronic dermatophytosis with giant cutaneous horns, suggesting a possible genetic link and highlighting successful treatment with antifungal medications.
October 2023 in “Medical records-international medical journal” In this study, researchers sought to explore whether there is a correlation between melasma and ABO/Rh blood types, using data from 100 patients with melasma and 1000 healthy controls.
In this study, researchers explored the heterogeneity of pigment cells in the human scalp anagen hair follicle bulb and discovered unexpected subpopulations of melanocytes, including immature SOX10-negative cells, highlighting potential non-melanogenic roles or transitional migratory functions that require further investigation.
March 2026 in “International Journal of Innovative Technologies in Social Science” This review highlights advancements in vitiligo treatment, noting improved diagnostic techniques and the emergence of targeted therapies like Janus Kinase inhibitors, which may offer more effective management of this complex autoimmune skin disorder.
260 citations
,
January 2020 in “Nature” Stress can cause hair to turn gray by depleting stem cells.
August 2023 in “Journal of Investigative Dermatology” Senescent melanocytes in nevus skin boost hair growth.
30 citations
,
December 2001 in “Experimental dermatology” This study found that gonadal steroid hormones influence alopecia areata in C3H/HeJ mice, with estradiol promoting progression and dihydrotestosterone conferring resistance to disease onset.
7 citations
,
April 2011 in “Expert review of dermatology” This article reviews practical approaches for managing dermatologic conditions in patients with skin of color and reports no new clinical findings.
March 2026 in “International Journal of Science and Research (IJSR)” This study reviews melatonin's diverse roles in dermatology, highlighting its potential to protect skin from UV damage and oxidative stress, enhance DNA repair, and influence hair follicle cycling, suggesting therapeutic applications in skin care and hair renewal.
5 citations
,
September 2015 in “Nepalese journal of ophthalmology” This case report highlights an 11-year-old girl with dermatopathia pigmentosa reticularis, identifying associated Salzmann's nodular degeneration of the cornea and emphasizing the need for a multidisciplinary management approach.
10 citations
,
February 2006 in “Archives of dermatology” A man's chest hair turned white after a shingles infection, possibly due to virus-damaged pigment cells.
March 2023 in “Journal of Cosmetic Dermatology” The researchers in this study described the use of trichoscopy to assist in diagnosing aplasia cutis congenita of the scalp in a dark-skinned newborn, noting that trichoscopic findings can differ from those seen in light-skinned patients, yet remain a valuable diagnostic tool.
September 2024 in “Pigment International” Results are not reported in this abstract; it discusses recent advancements in understanding vitiligo's pathogenesis, treatment, and comorbidities, emphasizing emerging areas like gut microbiome involvement and highlighting the disease's reclassification as a systemic condition with evolving therapies.
October 2019 in “Postgraduate Medical Journal” This case report describes a patient with pellagrous dermatitis related to chronic alcoholism, whose symptoms resolved within two weeks following treatment with nicotinamide, vitamin B12, and thiamine.
21 citations
,
November 2023 in “International Journal of Molecular Sciences” This ex vivo study reported that melatonin significantly improved certain aging biomarkers in aged human skin, including reduced mTORC1 activity, increased fibrillin-1, and enhanced collagen and elastic fiber organization, though other key biomarkers remained unchanged.
October 2021 in “European Journal of Dermatology” In this study, the researchers reported that calcipotriol pre-treatment made photodynamic therapy more effective and safe than conventional treatment for actinic keratosis on the scalp, improving long-term clearance rates, especially for Grade II lesions. However, they suggested larger trials are necessary to corroborate these findings.