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The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Fat tissue extract may help treat vitiligo by reducing cell stress and promoting skin repair.

Researchers found that certain lipids, especially vitamin D3, are lower in prematurely grey hair than in pigmented hair.

A new gene mutation may allow some piebaldism patients to regain skin color in white patches.

Narrowband UVB treatment increases certain gene expressions in psoriasis skin and improves symptoms.

Men with less sun-sensitive skin have lower PSA levels, while men with more sun-sensitive skin have higher PSA levels.

Scanning electron microscopy revealed four distinct hair root shapes in alopecia areata, suggesting a less invasive diagnostic method.

Gray hair can potentially be reversed, leading to new treatments.

Topical vitamin D is effective in treating vitiligo with few side effects.

Erdr1 could be a new marker for diagnosing hair loss.

Alopecia areata is an autoimmune disease with genetic links, treatable with certain medications, and can affect mental health.

People with certain skin diseases have higher levels of the hormone prolactin in their blood.

Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.

Alopecia areata patients have higher levels of certain immune receptors, suggesting new treatment possibilities.

PPAR-γ may be a key target for treating alopecia areata and other skin conditions.

SH-MSCs gel reduced IL-6 and increased TGF-β, suggesting it could treat alopecia.

People with premature hair graying have an imbalance between harmful and protective molecules in their body, hinting that antioxidants might help.

The model can effectively test gene functions and drug responses in human skin.

Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

New methods for skin and nerve regeneration can improve healing and feeling after burns.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Most patients with chronic kidney disease have skin problems, which get worse as the disease progresses, and dialysis doesn't greatly reduce these issues.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.

Men's hair loss is caused by hormones and genes, and can be treated with medication and surgery, while graying is due to aging and has no prevention except dyeing.