71 citations
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October 2013 in “Experimental Dermatology” This review discusses the similar immune pathways and genetic risk factors of vitiligo and alopecia areata but reports no new clinical findings, emphasizing the potential for shared treatment research.
5 citations
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June 2012 in “Journal of Investigative Dermatology” Harris et al. describe a new mouse model for vitiligo, where interfollicular melanocytes are retained and melanocyte-targeting immune responses are simulated, aiding the development of immunomodulatory therapies.
2 citations
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January 2002 in “Clinics in Dermatology” This review details the characteristics, associations, and differential diagnoses of vitiligo and reports no new clinical findings.
1 citations
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January 2023 in “Przegla̧d dermatologiczny” This review discusses the role of zinc in skin physiology related to vitiligo and reports no new clinical results; the authors emphasize its potential in pathogenesis and treatment.
October 2025 in “Journal of Investigative Dermatology” This review highlights the critical role of iron in skin functions and suggests potential dermatologic therapies targeting the iron-skin axis.
4 citations
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August 2013 in “Case reports in dermatology” This case report describes a patient in whom vitiligo was induced by diphenylcyclopropenone treatment for alopecia universalis, highlighting the potential overlap of susceptibility genes between the two conditions.
January 1990 in “Springer eBooks” Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.
5 citations
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August 2012 in “Archives of Dermatology” This case report describes a man's permanent skin and hair whitening, and generalized anhidrosis following allogeneic stem cell transplant, linked to immune-mediated destruction of melanocytes.
This case report describes perifollicular melanocyte regeneration in the affected skin of a patient with bullous pemphigoid, highlighting an underreported aspect of the condition in skin of color patients, and emphasizing the need for increased awareness and earlier diagnosis in this demographic.
1 citations
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April 2025 in “Pigment Cell & Melanoma Research” This article reviews the underlying mechanisms of segmental vitiligo with white hair, focusing on skin and hair follicle melanocytes, and proposes potential targets for treatment, highlighting neuroendocrine factors as possible contributors to the condition.
December 2025 in “Dermatology Reports” This source describes vitiligo as a chronic condition marked by the loss of skin pigmentation and discusses leukotrichia, a feature affecting 10% to 60% of cases, which arises from melanocyte loss in hair follicles and appears as well-defined white patches on the skin.
June 2025 in “Academic Medical Journal” This review discusses the complex etiology and pathogenesis of vitiligo, noting challenges in treatment effectiveness and relapse, and reports no new clinical results.
December 2021 in “Figshare” This review discusses recent advancements in targeted therapies for vitiligo, including JAK inhibitors and mesenchymal stem cells, and highlights the need for further research.
1 citations
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May 2017 in “Journal of Stem Cell Research & Therapeutics” This review discusses current and potential approaches using stem cells for treating hypopigmentation disorders like vitiligo but does not present new clinical findings.
March 2026 in “International Journal of Innovative Technologies in Social Science” This review highlights advancements in vitiligo treatment, noting improved diagnostic techniques and the emergence of targeted therapies like Janus Kinase inhibitors, which may offer more effective management of this complex autoimmune skin disorder.
July 2025 in “Pigment International” This case report highlights a 40-year-old Indian male diagnosed with follicular vitiligo, presenting as graying hair and depigmented patches, and emphasizes the importance of distinguishing this rare variant from similar conditions like alopecia areata due to its unique presentation.
61 citations
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December 2021 in “Frontiers in Cell and Developmental Biology” This review discusses progress in targeted therapies for vitiligo, focusing on Janus kinase inhibitors and the potential of mesenchymal stem cells, but reports no new clinical results.
11 citations
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August 1987 in “Archives of Dermatology” In this study, researchers found that Langerhans' cells likely do not play a role in the depigmentation process in C57Bl/Ler-vit.vit mice, as their number was normal during depigmentation and highest afterward.
This chapter reviews recent developments in vitiligo research, highlighting the role of melanocyte stem cell differentiation and oxidative stress in its management, but reports no new clinical results.
2 citations
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August 1987 in “Archives of Dermatology” In this study, researchers concluded that Langerhans' cells are likely uninvolved in depigmentation during vitiligo in C57Bl/Ler-vit vit mice, as their numbers were normal during depigmentation and increased afterward.
This study describes vitiligo as a chronic disorder where genetic, environmental, and immune factors contribute to skin depigmentation, with associations to other autoimmune diseases and potential links to oxidative stress.
63 citations
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December 1988 in “International Journal of Dermatology” Vitiligo causes white skin patches and is linked to autoimmune issues.
10 citations
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February 2012 in “Journal of Clinical Investigation” This review discusses advancements in understanding the biology and pathology of the epidermis and hair follicles, reporting no new clinical results but highlighting the synergy between research and dermatologic patient care.
28 citations
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July 2005 in “International Journal of Dermatology” Vitiligo is caused by the immune system attacking skin pigment cells.
In this case study, donor lymphocyte infusions effectively eradicated measurable residual disease in a patient with relapsed acute myeloid leukemia after hematopoietic cell transplantation, while side effects included the development of vitiligo and alopecia areata, likely due to chronic graft-versus-host disease.
January 2020 in “JAAD case reports” This article reviews current understanding of frontal fibrosing alopecia and lichen planopilaris, highlighting increasing incidence and unclear pathogenesis, and emphasizes the role of inflammatory destruction of hair follicular stem cells; it reports no new clinical findings.
2 citations
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September 2022 in “Bioscientia medicina” This literature review highlights the effectiveness of topical vitamin D (e.g., calcipotriol, calcitriol) in treating vitiligo, emphasizing its role in melanogenesis and as an immunomodulator, either alone or combined with topical corticosteroids, offering minimal side effects.
72 citations
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November 1997 in “Clinics in dermatology” This review discusses the potential autoimmune etiology of vitiligo and its association with other autoimmune diseases but provides no new research findings; the authors highlight various treatment options.
November 2025 in “The Journal of Dermatology” This review summarizes recent pathological discoveries related to chemical leukoderma and chemical-induced vitiligo, especially focusing on rhododendrol, a chemical responsible for a significant outbreak affecting around 20,000 individuals in Japan and Asia.
41 citations
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December 2018 in “Experimental Dermatology” This review explores recent findings on the roles of melanocyte and melanocyte stem cells in the hair follicle, highlighting their importance for skin health and potential applications in regenerative medicine, but reports no new clinical results.