Pathogenesis of Chemical Leukoderma and Chemical-Induced Vitiligo

    November 2025 in “ The Journal of Dermatology ”
    Y. Kuroda, Lingli Yang, Ichiro Katayama
    Studysummary This review summarizes recent pathological discoveries related to chemical leukoderma and chemical-induced vitiligo, especially focusing on rhododendrol, a chemical responsible for a significant outbreak affecting around 20,000 individuals in Japan and Asia.
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    Research cited in this study 1

    1. Immunohistopathological Analysis of Frizzled-4-Positive Immature Melanocytes from Hair Follicles of Patients with Rhododenol-Induced Leukoderma Journal of dermatological science · 2015