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Lovastatin doesn't improve lower urinary tract symptoms treatment.

The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.

Tadalafil is effective for treating urinary symptoms in men with BPH.

Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

New treatments for male hypogonadism are effective and should be personalized.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

The document concludes that better research methods are needed in men's sexual health to provide stronger evidence and improve patient care.

Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.

Finasteride lowers risk of urinary issues and surgery by over 50% in 4 years.

Dutasteride is effective for treating prostate enlargement and reducing related surgery risk, but is not approved for preventing prostate cancer.

Certain drugs that block specific enzymes can help treat prostate diseases.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

Rats had lasting erectile problems after stopping a certain medication.

Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Stopping alpha-blocker medication after 6-9 months is safe and effective for most patients with bladder outlet obstruction.

Finasteride helps reduce prostate size and symptoms in BPH but is less effective than terazosin and works best for larger prostates.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Most postmenopausal women experience significant skin changes and various skin conditions.