Associations Between Semen Quality and Lower Urinary Tract Symptoms in Aging Males

    October 2010 in “ Journal of Men's Health ”
    AusmeesK., ZarkovskiM., TimbergG., KorrovitsP., PunabM.
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    TLDR The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.
    The document from 13 years ago reviewed the effectiveness of 5α-reductase inhibitors in treating androgenetic alopecia and benign prostatic hyperplasia (BPH), noting their ability to prevent hair loss and improve urinary symptoms and prostate size in older men. However, it also highlighted significant adverse effects, including sexual dysfunction, behavioral changes, and cardiovascular events. Some side effects, such as reduced libido, erectile and ejaculatory dysfunction, and emotional issues, could be persistent or irreversible, negatively affecting quality of life. The conclusion emphasized the need for caution when prescribing these drugs and the importance of discussing potential adverse effects and alternative treatments with patients before starting therapy.
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