Higher Levels of Serum Uric Acid Are Significantly Associated with Lower Incidence of Lower Urinary Tract Symptoms in Healthy Korean Men

The study involving 101,091 healthy Korean men found that higher serum uric acid (SUA) levels were associated with a lower incidence of significant lower urinary tract symptoms (LUTS). Men with SUA levels of ≥9.5 mg/dL had a reduced risk of developing LUTS compared to those with levels <5.5 mg/dL, with an adjusted hazard ratio of 0.77. The research suggested a potential protective role of SUA against LUTS, although further investigation was needed to understand the underlying biological mechanisms. The study was conducted without external funding and adhered to ethical guidelines, using de-identified data from routine health checkups.