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Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.

Some steroid-induced health issues in rodents improved after stopping treatment, but hair loss and eye problems did not.

A mix of Polygonatum sibiricum and Nelumbinis semen may ease menopause symptoms with fewer side effects.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

Skin cysts might help advance stem cell treatments to repair skin.

Inactive hair follicle stem cells help prevent skin cancer.

Deleting MED1 in skin cells causes hair loss and skin changes.

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.

The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.

Geriatric Julia Creek dunnarts often suffer from reproductive and skin diseases, impacting conservation efforts.

Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.

Medroxyprogesterone injections caused hair regrowth in some dogs with alopecia X.

The conclusion is that different types of hair loss in dogs and cats can be cosmetic or serious, and affected animals should not be bred.

Spironolactone can cause side effects like high potassium levels and breast enlargement, and patients need careful monitoring.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.

ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.