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Finasteride affects prostate weights and pituitary activity differently with age.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Exposure to the hair loss drug finasteride during pregnancy can cause genital anomalies in male babies, but not in female babies. It's best to avoid this drug in women who could potentially become pregnant.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Finasteride exposure harms tadpole reproduction and hormone balance.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Finasteride may cause slight depression and anxiety.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.