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Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The link between physical signs of high male hormones and hormone levels in women with PCOS changes with age.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Birth control pills can cause skin issues but may help with acne and hirsutism, and choosing the right type can minimize side effects.

TIP39 and PTH2R help control calcium levels and skin cell development.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Mouse genital development depends on male or female hormones for specific features.

Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.

Castration is preferred for non-breeding male dogs with BPH, but other treatments are available with specific pros and cons.

Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.

The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.

There are many treatments for common hair loss, but more trials are needed to decide which are best.

Chromosomal differences affect how muscle cells respond to testosterone.

TURP is the best treatment for BPH, but some patients prefer medications like alpha-blockers and finasteride.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Women with PCOS in North China often have hirsutism and acne, with hirsutism linked to metabolic issues.

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.