131 citations,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
129 citations,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
87 citations,
January 2016 in “Development” Blocking β-catenin in skin cells improves hair growth during wound healing.
81 citations,
January 2006 in “Journal of cellular physiology” Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.
50 citations,
September 2014 in “Stem cell reports” BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
41 citations,
July 2009 in “International Journal of Trichology” 58% of men aged 30-50 have hair loss, with severity increasing with age.
27 citations,
October 1999 in “Experimental and Molecular Pathology” Stump-tailed macaque best for researching hair loss causes and treatments.
23 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.
19 citations,
March 2003 in “Journal of Investigative Dermatology” Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.
17 citations,
September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.
15 citations,
February 2008 in “Annals of plastic surgery” Most patients were satisfied with diode laser hair removal and experienced no long-term side effects.
15 citations,
February 1999 in “The anatomical record” Some mutant mice have hair with abnormal cross-linking, mainly in the cuticle, not affecting other hair parts.
12 citations,
November 2003 in “Journal of the American Academy of Dermatology” Topical diphencyprone helped regrow hair in mice and rats with a condition similar to human hair loss.
12 citations,
September 2002 in “Epilepsia” Monitoring new epilepsy drugs after they're sold is crucial to find rare and long-term side effects that initial tests might miss.
11 citations,
June 2016 in “npj Regenerative Medicine” The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.
5 citations,
September 2005 in “Dermatologic Surgery” Using a polarized LED magnifier during hair transplants eases recipient site creation and reduces eye strain but doesn't improve graft creation or placement.
1 citations,
March 2006 in “Dermatologic Surgery” Using a polarized LED magnifier during hair transplants makes creating recipient sites easier and may increase hair density.
June 2020 in “Annals of the Rheumatic Diseases” Patients with Systemic Sclerosis have much higher levels of GDF-15, which could help predict organ involvement and guide treatment.
April 2017 in “Plastic surgical nursing” Platelet-rich plasma (PRP) is an effective treatment for hair loss that involves scalp injections and requires ongoing maintenance.
September 2013 in “Science” Certain astrocytes can protect the brain and improve recovery after a stroke, and a hair loss drug might reduce cancer spread.
September 2013 in “Science” Human stem cells can aid stroke recovery, research experiences boost students' career aspirations, minoxidil may reduce cancer spread, a molecule can slow tumor growth, a protein affects water flow in cells, magnesium behaves differently at tiny scales, and a new method detects slow-moving objects.
September 2013 in “Science” Undergraduate research experiences boost students' research skills, confidence, and career aspirations.
September 2013 in “Science” Special astrocytes improved learning and memory in rats after a stroke.
September 2013 in “Science” Special astroglia cells improved stroke recovery in rats, a hair growth drug reduced cancer spread, and tiny magnesium structures were more easily shaped.
September 2013 in “Science” The document concludes that human astrocytes aid stroke recovery, research confidence affects student career aspirations, collagen affects cancer spread, a microRNA suppresses brain cancer growth, calmodulin regulates water channels, and small magnesium pieces deform differently.
July 2012 in “The Journal of Urology” Testosterone increases muscle mass regardless of DHT conversion blocking.
November 2011 in “Pediatric dermatology” Marie-Unna Hereditary Hypotrichosis is a rare genetic condition causing sparse hair growth, requiring specific recognition for proper care.
May 2019 in “Journal of the Dermatology Nurses’ Association” Folliculitis decalvans mainly affects middle-aged African American men and is treated with antibiotics.
1308 citations,
March 1998 in “Journal of bone and mineral research” The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
480 citations,
August 2014 in “Nature Biotechnology” Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.