Slowly Does It
September 2013
in “
Science
”
TLDR Special astrocytes improved learning and memory in rats after a stroke.
The document discusses several scientific findings, including a study by Jiang et al. on the therapeutic potential of astrocytes derived from human embryonic stem cells for stroke recovery. The study found that a subpopulation of astroglia expressing the transcription factor Olig2 had strong neuroprotective effects against oxidative stress and glutamate toxicity in vitro. When transplanted into rats that had suffered global cerebral ischemia, these Olig2+ astroglia promoted increased synaptogenesis and improved learning and memory. The study suggests that the differential expression of growth factors and other related molecules may explain the enhanced recovery facilitated by this specific astroglia population. Additionally, the document briefly mentions other research topics, including the role of self-efficacy in undergraduate research experiences, the molecular events in cancer metastasis, the relationship between NFIA and miR-223 in gliomas, the regulation of membrane channels by calmodulin, and the mechanical properties of magnesium at the nanoscale. However, the document does not provide specific details on the number of participants or subjects in the mentioned studies, except for the undergraduate research experience study, which involved 156 students.