Highway Deconstruction
September 2013
in “
Science
”
TLDR The document concludes that human astrocytes aid stroke recovery, research confidence affects student career aspirations, collagen affects cancer spread, a microRNA suppresses brain cancer growth, calmodulin regulates water channels, and small magnesium pieces deform differently.
The document discusses several scientific findings, including the potential of astrocytes derived from human embryonic stem cells in stroke recovery, the role of research self-efficacy in undergraduate research experiences, the importance of collagen networks in cancer metastasis, the relationship between NFIA and miR-223 in gliomas, the regulation of membrane channels by calmodulin, and the deformation behavior of magnesium at the nanoscale. Specifically, it highlights a study by Jiang et al. where rats with hippocampal transplants of human Olig2+ astroglia showed improved recovery after cerebral ischemia. Another study by Adedokun et al. involving 156 students found that research self-efficacy mediates the relationship between research skills and aspirations for research careers. Eisinger-Mathason et al. demonstrated that inhibiting PLOD2 with minoxidil reduced metastasis in mouse models of sarcoma. Glasgow et al. documented the suppression of glioma cell growth by miR-223 through repression of NFIA. Reichow et al. showed how calmodulin restricts the dynamics of aquaporin AQPO monomers, affecting water permeability. Lastly, Yu et al. observed that magnesium samples below 100 nm exhibited increased plastic deformation due to activation of nonbasal planes.
