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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.

Mesenchymal stem cells may help treat hair loss by improving hair cell growth and reducing inflammation.

Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.

A girl with lupus and trisomy X has a higher risk of bone problems like avascular necrosis and osteoporosis.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

Pilose antler extracts help hair growth by activating hair follicle stem cells.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Mobile phone radiation may cause DNA damage in human ear hair follicle cells.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

CD8+ T cells are involved in alopecia areata and may cause disease relapse.

New cancer treatments aim to reduce side effects and improve effectiveness.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Cyclosporin A promotes hair growth in mice and increases a protein linked to hair growth, but it may not work the same way in humans.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

A 3-year-old girl developed scurvy symptoms that improved with vitamin C but relapsed when supplementation stopped.

Alopecia areata patients show unique protein activity patterns, suggesting imbalanced signaling pathways.

Down Syndrome patients with Alopecia Areata often have hypothyroidism and specific immune abnormalities.

Robotic hair transplantation with AI offers more reliable, precise, and efficient hair restoration.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

Selective breeding can enhance immunity in dairy cattle.

Histone modification is key in treating chronic inflammatory skin diseases.