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Baricitinib helps regrow hair in adults with severe alopecia better than a placebo and is approved for treatment, but long-term effects are still unknown.

Kampo medicine can help treat general fatigue from long COVID.

Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.

New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.

Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.

Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Probiotics show promise for health benefits but need more research to understand how they work.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

A woman with severe hair loss was successfully treated with the drug adalimumab.

Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

Proxalutamide improved recovery, lowered death rates, and reduced hospital stay for COVID-19 patients.

Hair cortisol is a reliable stress indicator in cattle but may not be valid for pigs.

New targeted immunotherapies are improving treatment for inflammatory skin diseases.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.

Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

Zinc is important for skin health, and supplements can help treat various skin and hair disorders, but more research is needed for conditions like psoriasis and vitiligo.

Adenosine receptors could be promising targets for treating inflammatory skin diseases like psoriasis.

Deoxycholic acid is FDA-approved for reducing submental fat, but its mechanisms are not fully understood.

Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

Digital gangrene can be an initial symptom of late-onset systemic lupus erythematosus.

Sulforaphane from broccoli may help treat certain cancers, hormone issues, and hair loss.

Extracellular vesicles show promise for treating psoriasis by reducing inflammation and skin lesions.