Search

for
Search:

Sort by

Research

90-120 / 1000+ results

research Two siblings with a novel nonsense mutation, p.R50X, in the vitamin D receptor gene

8 citations , March 2011 in “Endocrine”

In this study, researchers identified a novel p.R50X mutation in the vitamin D receptor gene, linked to hereditary vitamin D-resistant rickets in two siblings.

research Vitamin D: More Than a “Bone-a-Fide” Hormone

276 citations , April 2003 in “Molecular endocrinology”

This review explores the diverse physiological roles of the vitamin D endocrine system, discussing current research on receptor structure, transcription details, murine models, and alternative receptors, but reports no new findings.

research Hairless Suppresses Vitamin D Receptor Transactivation in Human Keratinocytes

78 citations , November 2005 in “Endocrinology”

This study found that Hairless (Hr) acts as a corepressor of the vitamin D receptor (VDR) in human keratinocytes, blocking the action of vitamin D on keratinocyte differentiation.

research How Biotin Induces Misleading Results in Thyroid Bioassays: Case Series

5 citations , May 2019 in “Cureus”

In this study, the authors reported that taking 20 mg or more of biotin can interfere with thyroid function tests, potentially leading to false diagnoses of conditions like Grave's disease.

research Hair & Cutaneous Development

January 2012 in “Journal of Investigative Dermatology”

The document presented various studies on hair and cutaneous development, revealing insights into hair biology and potential therapeutic targets for hair-related conditions. Key findings included the role of stem cells and their niches in hair regeneration, the impact of TACE/ADAM17 depletion on alopecia, and the expression of somatostatin in hair follicles. Research on genetic factors, such as CYLD mutants and P-cadherin, highlighted their importance in hair growth and pigmentation. Studies on hair aging identified genes involved in hair loss in women over 40. Additionally, the potential of keratinocyte precursors from iPS cells for hair follicle regeneration and the effectiveness of a parathyroid hormone analog in reversing chemotherapy-induced alopecia were explored. The document also discussed the role of cholesterol biosynthesis in cicatricial alopecia, the necessity of Wnt signaling for hair follicle initiation, and the effects of ATP-sensitive potassium channel blockers on hair growth. These findings collectively advanced the understanding of hair growth, alopecia treatment, and skin regeneration.

research Iron Deficiency in Menstruating Adult Women: Much More than Anemia

14 citations , January 2020 in “Women's health reports”

This study found that iron therapy improved nonhematological symptoms and cognitive function in women with iron deficiency anemia, highlighting the need for attention to these symptoms in improving quality of life.

research Investigation of Transcriptional Gene Profiling in Normal Murine Hair Follicular Substructures Using Next-Generation Sequencing to Provide Potential Insights into Skin Disease

1 citations , February 2016 in “Cell Transplantation”

In this study, researchers found that hair follicles and dermal fibroblasts, including dermal papilla cells, supported sustained hair growth in transplanted murine models, with RNA-seq analysis revealing active signaling pathways and gene expression patterns.

research Alopecia with Vitamin D-Dependent Rickets Type 2 A: A Case Report

January 2024 in “Clinical, cosmetic and investigational dermatology”

In this case report, a four-year-old girl was diagnosed with vitamin D-dependent rickets type II, manifesting as diffuse alopecia, frontal bossing, hypoplastic teeth, and skin-colored papules, due to a genetic mutation causing resistance to 1.25-dihydroxy vitamin D.

research Novel TMEM173 Mutation and the Role of Disease Modifying Alleles

47 citations , December 2019 in “Frontiers in immunology”

This study identified a novel G207E STING mutation associated with severe inflammatory symptoms and suggested that common polymorphisms in TMEM173 and IFIH1 may modify the phenotype in affected individuals.

Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables

research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables

86 citations , December 2001 in “Experimental dermatology”

This review classifies mutant mice with hair abnormalities into six categories, providing an annotated table that serves as a reference for understanding the molecular controls of hair growth.

research FOXN1 Deficiency: from the Discovery to Novel Therapeutic Approaches

33 citations , September 2017 in “Journal of clinical immunology”

This review summarizes recent findings on FOXN1's essential role in thymus and skin biology and discusses emerging therapeutic approaches for immune disorders with athymia, but reports no new clinical results.

research Update on Drugs Used to Treat Endocrine Diseases in Small Animals

20 citations , September 2006 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice”

This article reviews new drug therapies for endocrine disorders, discussing specific treatments such as trilostane for hyperadrenocorticism and various insulins for diabetes mellitus, but it reports no new clinical findings.

research Distribution of 1,25-dihydroxyvitamin D3[22-oxa] in vivo receptor binding in adult and developing skin

15 citations , January 1995 in “Archives of dermatological research”

In this study, OCT showed strong nuclear binding in certain skin cells, suggesting similar genomic effects to vitamin D with potential therapeutic benefits due to its lower calcaemic effect.

research Endocrinology, Brain, and Pituitary Gland

2 citations , November 2013 in “Elsevier eBooks”

This chapter discusses the role of hormones in regulating reproductive biology and outlines how the endocrine system, particularly the brain and pituitary gland, controls these hormonal processes.

research Evaluation of Serum Vitamin D Levels in Patients with Vitiligo

January 2023 in “Pakistan Armed Forces Medical Journal”

This study found that patients with vitiligo had significantly lower serum vitamin D levels compared to healthy controls.

research Polyglandular Syndrome Type 1 Complicated with Dilated Cardiomyopathy: A Case Report

April 2024 in “Research Square (Research Square)”

This case report describes a 27-year-old male with autoimmune polyglandular syndrome type 1, characterized by symptoms including fever, dysarthria, dysphagia, oral candidiasis, nail dystrophy, alopecia, hypoparathyroidism, and dilated cardiomyopathy. The study highlights unique bilateral symmetrical brain calcifications and underscores the syndrome’s diverse manifestations.

research The Role of Vitamins and Minerals in Hair Loss: A Review

134 citations , December 2018 in “Dermatology and Therapy”

This review discusses the potential role of vitamins and minerals in managing non-scarring alopecia but reports no clinical results; the authors advocate for further controlled trials to explore these relationships.

research Molecular Genetic and Endocrine Mechanisms of Hair Growth

51 citations , January 2003 in “Hormone Research in Paediatrics”

This review discusses hormonal influences on hair growth and suggests that understanding hormone-gene interactions may improve treatment of hirsutism and alopecia, but reports no new clinical findings.

Pregnancy and Skin: Changes and Dermatoses

research Pregnancy and Skin

26 citations , June 2012 in “The Journal of Obstetrics and Gynecology of India”

This review discusses various skin changes during pregnancy, noting that while most are benign and resolve after childbirth, some may require careful medical management for the safety of the mother and fetus; it reports no new results.

research Friends Turned Foes: Angiogenic Growth Factors beyond Angiogenesis

24 citations , October 2017 in “Biomolecules”

This review discusses the broader roles of angiogenic factors, like VEGFs and FGFs, beyond angiogenesis, highlighting their involvement in various biological and pathological processes.

research Vitamin D activates type A natriuretic peptide receptor gene transcription in inner medullary collecting duct cells

17 citations , April 2007 in “Kidney international”

This study found that 1,25 dihydroxyvitamin D3 significantly increased the expression and activity of vasculoprotective natriuretic peptide receptor-A in cultured inner medullary collecting duct cells, suggesting a potential mechanistic role in cardiovascular and renal benefits.

research The role of anemia and vitamin D levels in acute and chronic telogen effluvium

11 citations , January 2011 in “Turkish Journal of Medical Sciences”

This study found that iron deficiency anemia is a key factor in the development of telogen effluvium, and higher 25-hydroxyvitamin D3 levels in TE patients may be linked to increased UV exposure.

research Hemiagenesis of the thyroid gland detected by coincidence—what is the clinical relevance?

7 citations , October 2020 in “Wiener medizinische Wochenschrift”

This paper presents a case study of a 21-year-old male with thyroid hemiagenesis, where the left thyroid lobe and isthmus are absent, and discusses the anomaly's potential clinical consequences based on existing literature.

Epimedium Brevicornum Maxim Extract Enhances Melanin Biosynthesis and Melanosome Biogenesis/Transfer

research Epimedium brevicornum Maxim. Extract exhibits pigmentation by melanin biosynthesis and melanosome biogenesis/transfer

6 citations , September 2022 in “Frontiers in pharmacology”

In this study, Epimedii Folium extract was found to enhance melanin production and promote pigmentation through mechanisms involving the MAPK/ERK1/2 pathway in both in vitro and in vivo models.

research Spatial and temporal control of laminin-511 and -332 expressions during catagen

6 citations , April 2010 in “Journal of Dermatological Science”

This study observed that downregulation of laminin-511 plays an important role in hair regression during the catagen stage in mice.

The Impact of Exogenous Vitamin D on Thyroid Autoimmunity in Euthyroid Men with Autoimmune Thyroiditis and Early-Onset Androgenic Alopecia

research The impact of exogenous vitamin D on thyroid autoimmunity in euthyroid men with autoimmune thyroiditis and early-onset androgenic alopecia

5 citations , June 2021 in “Pharmacological Reports”

This study suggests that vitamin D treatment may be less effective in reducing thyroid autoimmunity for euthyroid men with early-onset androgenic alopecia compared to other men with autoimmune thyroiditis.

research Abstracts of 42nd National Conference of Association of Clinical Biochemists of India (ACBICON 2015)

1 citations , November 2015 in “Indian Journal of Clinical Biochemistry”

The conference presented findings on how vitamin D levels, genetic factors, and lifestyle choices like smoking and yoga affect various health conditions and diseases.

research Very Late Onset "Trichotillomania": A Case Report

December 2018 in “Meandros medical and dental journal”

This case study describes a male patient with very late-onset trichotillomania, highlighting the condition's potential association with comorbid depression.

Health Is Wealth and Wealth Is Pugos Nutrition

research Health is Wealth & Wealth is Pugos Nutrition

January 2020 in “Asian journal of applied science and technology”

This source provides an overview of the dietary recommendations for macronutrient intake and the benefits of plant-based diets, including meeting essential amino acid needs through combining plant proteins and the advantages of consuming complex carbohydrates and adequate fiber for health.

research Extraskeletal actions of vitamin D

119 citations , July 2016 in “Annals of the New York Academy of Sciences”

This review examines the impact of vitamin D signaling in extraskeletal tissues and notes that expected benefits from animal and cell studies have not been consistently replicated in human clinical trials.

← Previous page Next page →