Skin Manifestations of Chronic Kidney Disease
October 2015
in “
Actas Dermo-Sifiliográficas
”
chronic kidney disease renal pruritus end-stage CKD nephrogenic systemic fibrosis gadolinium-based contrast agents diabetes mellitus secondary hyperparathyroidism hemodialysis cinacalcet sodium thiosulfate parathyroidectomy vacuum dressing CKD itching kidney failure NSF contrast dye diabetes high parathyroid hormone dialysis Sensipar STS parathyroid surgery wound vacuum
TLDR Chronic kidney disease can cause skin problems that affect patient quality of life, and treating these conditions can improve outcomes.
The document from 2015 reviews skin conditions associated with chronic kidney disease (CKD), particularly in its end stages, and their impact on patient quality of life. It highlights severe renal pruritus, affecting 50-90% of end-stage CKD patients, as a condition associated with increased mortality. The review notes that nail examination can provide insights into albumin and urea levels and identifies nephrogenic systemic fibrosis as a preventable condition linked to gadolinium-based contrast agents. It also discusses comorbidities like diabetes mellitus and secondary hyperparathyroidism as causes for specific skin conditions. Treatments for these conditions include improving hemodialysis quality, medications like cinacalcet and sodium thiosulfate, and interventions such as parathyroidectomy and vacuum dressing. The document emphasizes the importance of effective treatment for CKD-related skin disorders to improve patient outcomes.
