Comparison of Cutaneous Manifestations in Chronic Kidney Disease With or Without Dialysis

    October 2010 in “ Postgraduate Medical Journal
    Deepshikha Khanna, Archana Singal, Om Prakash Kalra
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    TLDR Most patients with chronic kidney disease have skin problems, which get worse as the disease progresses, and dialysis doesn't greatly reduce these issues.
    The study investigated skin conditions in 200 patients with chronic kidney disease (CKD) at various stages and found that 96% had at least one dermatological issue. Xerosis was the most common, affecting 72%, followed by pigmentation changes (50%), pruritus (36%), infections (29%), and nail changes (64% in those on maintenance hemodialysis). The prevalence of these conditions increased with the severity of CKD, particularly in end-stage renal disease (ESRD), and dialysis did not significantly reduce these skin manifestations. The study suggests that managing these skin conditions with emollients, sunscreens, and nutritional supplements, as well as treating infections promptly, could improve patient outcomes. It also calls for further research to assess the long-term effects of dialysis on skin health in ESRD patients. Ethics approval was obtained for this peer-reviewed study.
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