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Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Different types of facial fat affect aging and treatment outcomes; more research is needed to enhance anti-aging procedures.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Melatonin improved mental health and metabolism in women with PCOS.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Fat cells are important for tissue repair and stem cell support in various body parts.

Quercetin may help with PCOS symptoms, but more research is needed.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.

People with Lichen Planus, especially with mucosal involvement, are more likely to have Metabolic Syndrome, which increases their risk for heart disease and diabetes.