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Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Sebocytes play a key role in controlling androgen levels in human skin.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

New effective scar treatments are urgently needed due to the current options' limited success.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

PEVs improve minoxidil skin penetration, increasing hair growth.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.