This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.
August 2025 in “Molecules” In this study, researchers using advanced chromatography and mass spectrometry techniques tentatively identified 132 chemical compounds in Justicia procumbens, including 54 lignans and 77 compounds reported for the first time, which may aid in pharmacological research and quality control of the plant.
46 citations
,
August 2019 in “Journal of Ethnopharmacology” This review compiles current information about Eclipta prostrata, traditional uses, and its promising pharmacological properties, like hepatoprotective and anti-inflammatory effects, but emphasizes that more research is needed to fully understand its mechanisms and ensure safety for clinical application.
October 2007 in “한방재활의학과학회지” This study found an imbalance in autonomic nervous system activity in patients with androgenetic alopecia, with increased sympathetic activity and decreased parasympathetic activity compared to a control group.
43 citations
,
September 2001 in “Scanning” Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.
May 2024 in “Ultramicroscopy” Atomic Force Microscopy is a more accurate way to assess hair damage and the effect of cosmetic treatments.
67 citations
,
February 2015 in “Life Sciences” This review discusses phytotherapy options for managing benign prostatic hyperplasia, noting some herbal agents show promise in trials for mild-moderate symptoms but more evidence is needed for others.
80 citations
,
April 2011 in “Plant physiology” This study suggests that the GPX-PDE1 and GPX-PDE2 genes in white lupin enhance root hair development and contribute to Pi limitation acclimation by facilitating glycerophosphodiester degradation.
27 citations
,
June 2023 in “Nature” In this study using genetic mouse models, researchers discovered that senescent melanocytes in nevi secrete osteopontin, which activates hair stem cells, enhancing hair growth; this process is mirrored in human hairy nevi, suggesting a potential therapeutic target for regenerative disorders.
4 citations
,
January 2020 in “Cells” This study found that the transcriptome of skin stem cells in mice changes significantly with age, revealing specific age-dependent biological programs and transcriptional hubs.
August 2023 in “International Journal of Molecular Sciences” This review discusses the use of human-to-mouse xenografting to study human skin processes in vivo, highlighting its importance for understanding skin regeneration and pathology while identifying knowledge gaps and challenges in applying these findings to human skin.
12 citations
,
March 2023 in “Processes” In this study, extracts from Chenopodium quinoa, Glycine max, and Malpighia emarginata demonstrated stability, low toxicity, and effective cleaning potential as surfactants in shampoo formulations, showing performance similar to or better than commercial shampoos in terms of surface and interfacial tension and sebum removal.
4 citations
,
June 2021 in “Powder Technology” This study developed finasteride-containing granules using a method that improved follicular targeting for androgenic alopecia and reported potential for easy industrial production.
3 citations
,
October 2023 in “Journal of Pain” In this exploratory study of trigeminal neuralgia patients undergoing microvascular decompression surgery, differential protein expression in plasma and cerebrospinal fluid was observed between responders and non-responders, suggesting potential biomarkers to predict surgical success and providing insights into the mechanisms of pain relief.
1 citations
,
June 2022 in “Pharmaceutics” This study found that paracellular transport significantly contributes to the intestinal permeability of minoxidil, suggesting its limited suitability as a Biopharmaceutics Classification System reference drug due to potential variability.
192 citations
,
March 2017 in “Cell host & microbe” The researchers reported that hair follicle development and commensal microbe colonization promote the accumulation of regulatory T cells in neonatal skin, with the Ccl20-Ccr6 pathway playing a key role in this process.
10 citations
,
March 2021 in “Skin health and disease” This review discusses dermatologic manifestations of COVID-19, highlighting the possibility that skin signs might be the initial indicators of infection, though it reports no new clinical results.
3 citations
,
May 2022 in “Oncogene” This study revealed that Vav2 and Vav3 play roles in regulating hair follicle bulge stem cells in normal conditions and cancer stem cell activation and remodeling in mice.
38 citations
,
April 2018 in “Psychopharmacology/Psychopharmacologia” In this study, socially defeated mice showed increased alcohol consumption, and CRF-R1 antagonism selectively reduced drinking in these mice, suggesting a potential treatment target for stress-related alcohol use disorders.
5 citations
,
February 2022 in “Stem cell reports” This study found that thymic stromal lymphopoietin (TSLP) promotes hair growth after skin injury by enhancing the proliferation of specific stem cells in hair follicles.
77 citations
,
July 2020 in “Cell” This study found that sympathetic nerves and arrector pili muscles form a niche that modulates hair follicle stem cell activity, revealing their role in hair follicle regeneration.
38 citations
,
October 2011 in “Analytical biochemistry” This study used proteomic techniques to analyze human hair proteins, revealing keratin heterogeneity and identifying posttranslational modifications, such as cysteine trioxidation and methylation.
This reference list, part of a book by Alex Gough, Alison Thomas, and Dan O'Neill, compiles citations from veterinary journals on various canine and feline health issues, but reports no new research findings.
24 citations
,
January 2014 in “The American Journal of Chinese Medicine” This review compiles data on Platycladus orientalis leaves, noting their diverse pharmacological activities and advocating for more research to clarify their traditional blood-cooling and hematostatic uses.
January 2023 in “Discovery immunology” T cells and bacteria in the gut and skin help maintain health and protect against disease.
1308 citations
,
March 1998 in “Journal of bone and mineral research” This review discusses the molecular role of the vitamin D receptor in regulating various biological actions such as bone mineralization and reports no new clinical results, highlighting the complexity of vitamin D's function in multiple tissues.
532 citations
,
August 2011 in “Journal of the American Academy of Dermatology” This article discusses the clinical presentation, histopathologic findings, and pathogenesis hypotheses of vitiligo without reporting new clinical results.
329 citations
,
January 1997 in “Journal of the American Academy of Dermatology” This study reports that progressive frontal fibrosing alopecia, a distinct and gradually stabilizing form of lichen planopilaris affecting elderly women and often involving eyebrow hair loss, lacks effective treatments.
295 citations
,
September 2006 in “Cell Cycle” This review discusses the role of the TOR pathway in aging and suggests that rapamycin could potentially target age-related diseases, but reports no new clinical results.
213 citations
,
June 2017 in “Rheumatology” This guideline outlines the management of systemic lupus erythematosus in adults but reports no new clinical findings.