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Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Minoxidil activates hair growth by being sulfated by P-PST in the human liver.

Germ-free rats need biotin for growth and have different vitamin metabolism compared to regular rats.

Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.

Women with PCOS often have liver disease, so liver health checks are important for them.

Finasteride doesn't affect omeprazole metabolism in Japanese people.

Albendazole treatment for echinococcosis can cause serious side effects and requires close monitoring.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.

ECM1-modified stem cells can effectively treat liver cirrhosis.

Finasteride and methadone don't increase advanced liver disease risk in HCV+ male veterans.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.

Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.

Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.

Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.

Professor Ma Shuanquan treats hair loss by using Chinese medicine to improve liver, spleen, and kidney health.

Long-term use of seizure medications can disrupt calcium metabolism, but this can be treated with vitamin D or UV light and does not affect seizure control.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Altering SSAT affects fat metabolism and body fat in mice.

Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

As of 1994, treatments for liver cancer had not significantly improved patient survival.

Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.

Origanum vulgare leaf extract reduces liver and kidney damage caused by finasteride in mice.