23 citations
,
March 2023 in “eLife” This study reveals that epidermal stem cell differentiation in mice involves dynamic transcriptional changes, with Keratin-10 transcription preceding gradual chromatin compaction shifts associated with differentiation.
48 citations
,
August 1981 in “American Journal of Veterinary Research” This study demonstrates that glucocorticoid hepatopathy in Beagle dogs led to rapid and lasting clinical, morphologic, and biochemical changes, which may aid in the future diagnosis and prognosis of similar conditions.
April 2026 in “International Journal of Advanced Biochemistry Research” This study assessed mice's hematology and serum enzymes under sodium arsenite toxicity and observed that Aegle marmelos fruit extract reduced liver and kidney damage, mitigating the toxin's effects by maintaining normal enzyme levels when both were administered together.
55 citations
,
July 1999 in “Clinics in Sports Medicine” This review discusses recent data on the use of anabolic-androgenic steroids and other steroid compounds and reports no new clinical results.
53 citations
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December 2012 in “Revista da Sociedade Brasileira de Medicina Tropical” In this study, liver transaminase levels and various symptoms persisted in some adult dengue patients even two months after diagnosis.
January 2026 in “Springer Link (Chiba Institute of Technology)” In this study, researchers synthesized silver nanoparticles using an extract from Mitracarpus scaber and found them to have significant hepatoprotective and anti-hyperplastic effects in rats, suggesting potential for treating liver injury and benign prostatic hyperplasia.
4 citations
,
October 2005 in “Pediatric Transplantation” This study identified that pediatric transplant recipients experience specific skin changes related to medication use, with unique conditions like ichthyosiform xerosis in kidney recipients and skin scaling with pellagroid appearance in bone marrow recipients.
7 citations
,
July 2020 in “Dermatologic therapy” This review discusses premature graying of hair, highlighting risk factors like smoking and vitamin deficiencies, and suggests that addressing underlying conditions may reverse the graying process.
August 2024 in “Indian Journal of Entomology” This study found that rabbits with mange showed significant declines in haemoglobin, PCV, and RBC count, alongside increased TLC and liver enzyme levels. Following treatment with ivermectin and proper management, recovery from the disease was observed.
10 citations
,
April 2019 in “Environmental Science and Pollution Research” In this study, selenium-rich diets enhanced antioxidant activity in aged mice, suggesting potential biological benefits, although further trials are needed to fully understand long-term risks and benefits.
17 citations
,
January 2021 in “Agrobiological Records” This study reported that allethrin caused dose-dependent toxico-pathological effects, including decreased feed intake, body weight, and blood parameters, and organ damage in adult male albino rats.
January 2024 in “Biological trace element research” In this study, isotretinoin treatment for acne vulgaris was associated with changes in plasma phosphorus, potassium, magnesium, and zinc levels, potentially affecting kidney function and contributing to side effects like fatigue and dry skin.
March 2024 in “Egyptian Journal of Veterinary Science” This study investigated the effects of nandrolone decanoate on adult rabbits and reported that administering 10 mg/kg for 15 days caused harmful histological changes in the heart, liver, and kidneys, including inflammation and tissue degeneration.
September 2022 in “Research Square (Research Square)” This study found that caffeic acid treatment mitigated the negative effects of acrylamide toxicity in Wistar rats by normalizing tissue and serological indices.
March 2022 in “Egyptian Academic Journal of Biological Sciences. E, Medical Entomology and Parasitology” This review examines the potential pathogenicity of Demodex mites in skin disorders, considering systemic factors like immunological imbalance and microbiome changes, but reports no new clinical findings.
61 citations
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April 2021 in “Frontiers in Medicine” This study found that hidradenitis suppurativa significantly impaired quality of life in German patients, with severity linked to skin and certain extra-cutaneous changes, but not reduced by surgical or conventional medicamentous treatments.
January 2026 in “E3S Web of Conferences” This study found that silver nanoparticles synthesized using Mitracarpus scaber extract showed potential hepatoprotective and anti-hyperplastic effects in rats, suggesting novel therapeutic strategies for managing liver injury and benign prostatic hyperplasia.
24 citations
,
May 2016 in “Stem Cell Reviews and Reports” This article reviews the roles and mechanisms of stem and progenitor cell migration in adult organs for tissue homeostasis and regenerative medicine, but reports no new experimental results.
3 citations
,
October 2020 in “International journal of radiation research” This study found that while flour irradiation disrupted the physiology of Tribolium confusum, it also caused significant weight loss and biochemical changes in rats fed on irradiated flour.
14 citations
,
October 2020 in “Journal of ethnopharmacology” This study found that both ethanol and aqueous extracts of Lepidium sativum seeds improved insulin signaling and reduced obesity-related metabolic changes in high-fat diet-fed rats, suggesting potential as a dietary supplement.
7 citations
,
January 2022 in “Animal Reproduction” This review examines rodent models to explore how maternal conditions like undernutrition, obesity, hypoxia, and androgen exposure affect fetal programming and metabolic outcomes in offspring, but presents no new clinical findings.
January 2025 in “Indian Journal of Experimental Biology” In this study, mice orally exposed to carbon-based nanoparticles for 30 days showed significant liver and kidney changes, behavioral alterations, and physiological disturbances, suggesting potential severe health risks due to the nanoparticles' slow clearance and formation of reactive oxygen species.
116 citations
,
October 1982 in “The Journal of Pathology” This study found that high-dose Cyclosporin A in rats led to significant functional and structural changes, including liver, kidney, and immune system alterations, along with behavioral and hematological effects.
February 2019 in “Americanae (AECID Library)” This study describes cases of diffuse alopecia and thyroid alterations in sheep, linking selenium and zinc deficiencies to decreased serum T3 and T4 concentrations and related skin conditions.
36 citations
,
July 1987 in “Journal of toxicology and environmental health” This study found that rats fed diets with heated corn or peanut oil showed signs of toxicity, including liver and kidney weight increases, diarrhea, and ceased spermatogenesis, compared to those consuming fresh oils.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study used a novel fluorescent tagging method in mice to observe collagen IV dynamics during hair follicle development, revealing that alterations in basement membrane turnover can influence epithelial progenitor cell behavior and organ morphology by affecting cell proliferation and movement.
2 citations
,
February 2016 in “African Journal of Traditional Complementary and Alternative Medicines” In this study, prolonged ingestion of linseed in rabbits was observed to be safe, showing no significant weight gain or anatomical anomalies in liver and kidney biopsies.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” This study found that women with PCOS displayed significantly higher activity of 5alpha-reductase, suggesting an additional role for liver and peripheral tissues in their androgen excess.
6 citations
,
October 2024 in “Reviews in Endocrine and Metabolic Disorders” In this review, researchers found that while hyper- and hypoprolactinemia in PCOS patients are linked to metabolic changes, intermediate prolactin levels might be protective, but more robust prospective studies and clinical trials are needed to confirm these findings and develop treatments.
January 2025 in “International Journal of Advancement in Life Sciences Research” This research found that crude leaf extracts of Calotropis gigantea caused significant oxidative stress and cellular damage in freshwater fish Danio rerio over 30 days, highlighting the toxicological risks of this plant despite its medicinal properties.