Clinical And Hepatic Evaluation In Adult Dengue Patients: A Prospective Two-Month Cohort Study

    December 2012 in “ Revista da Sociedade Brasileira de Medicina Tropical ”
    Ricardo Tristão Sá, Claire Fernandes Kubelka, Eliana Zandonade, Sônia Maria Oliveira Zagne, Natally de Souza Maciel Rocha, Luiza Oliveira Zagne, Nathalia F. Araujo, Beatriz Amin, Flávia Fazoli, Luíz José de Souza, Oswaldo Gonçalves Cruz, Rivaldo Venâncio da Cunha, Delso do Nascimento, Íris Bucher Froes, Rita Maria Ribeiro Nogueira
    TLDR Dengue symptoms and liver issues can persist for over two months, especially in men.
    This 2008 study in Brazil monitored 90 adult dengue patients over two months, revealing that 33.3% experienced persistent symptoms such as arthralgia, fatigue, weakness, anorexia, taste alteration, and hair loss. Elevated liver enzyme levels, particularly alanine aminotransferase (ALT), were noted, with males showing more severe elevations. Severe dengue was linked to prolonged anorexia and taste alteration, while prior dengue infection did not affect symptom duration. The study suggested that prolonged symptoms and liver dysfunction might be due to immunological mechanisms rather than the virus itself.
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